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Bioorganic Chemistry in Healthcare and Technology

  • Book
  • © 1991

Overview

Editors:
  1. Upendra K. Pandit

    1. University of Amsterdam, Amsterdam, The Netherlands

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    You can also search for this editor in PubMed   Google Scholar

  2. Frank C. Alderweireldt

    1. University of Antwerp (RUCA), Antwerp, Belgium

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 207)

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Table of contents (37 chapters)

  1. Front Matter

    Pages iii-xi
    Download chapter PDF

  2. Biogeneration of Aromas: Gamma and Delta Lactones from C-6 to C-12

    • Claudio Fuganti, Piero Grasselli, Massimo Barbeni
    Pages 1-17

  3. Catalytic Antibodies

    • Stephen J. Benkovic
    Pages 19-21

  4. Inhibition of Sterol Biosynthesis by Analogues of Carbenium Ion Intermediates

    • Maryse Taton, Pierre Benveniste, Alain Rahier
    Pages 23-37

  5. Molecular Modelling and Structural Databases in Pharmaceutical Research

    • Klaus Müller
    Pages 39-52

  6. Supramolecular Reactivity and Catalysis of Phosphoryl Transfer

    • Jean-Marie Lehn
    Pages 53-54

  7. Polymer Assisted Molecular Recognition: The Current Understanding of the Molecular Imprinting Procedure

    • Günter Wulff
    Pages 55-68

  8. The Chemistry of Lignin Biodegradation Catabolism of Veratryl Alcohol and its Methyl Ether

    • H. E. Schoemaker, U. Tuor, A. Muheim, H. W. H. Schmidt, M. S. A. Leisola
    Pages 69-86

  9. Studies on Plant Tissue Culture — Synthesis and Biosynthesis of Biologically Active Substances

    • James P. Kutney
    Pages 87-107

  10. NMR Studies Of complexes of L. Casei Dihydrofolate Reductase with Antifolate Drugs: Multiple Conformations and Conformational Selection of Bound Rotational Isomers

    • J. Feeney
    Pages 109-120

  11. Structure-Function Relationship of Gastrin Hormones: A Rational Approach to Drug Design

    • Evaristo Peggion, Maria Teresa Foffani, Stefano Mammi
    Pages 121-133

  12. Indirect Modelling of Drug-Receptor Interactions

    • Uli Hacksell, Anette M. Johansson, Anders Karlén, Charlotta Mellin
    Pages 135-147

  13. Production of Beta-Lactams: A Mixture of Organic Synthesis Processes and Enzymatic Processes

    • Svend G. Kaasgaard, Poul B. Poulsen
    Pages 149-160

  14. Mechanism of Action of β-Lactamases and DD-Peptidases

    • Jean-Marie Frère, Bernard Joris, Françoise Jacob, André Matagne, Didier Monnaie, Marc Jamin et al.
    Pages 161-170

  15. NMR Studies of the Enzyme Mechanisms of Vitamin B12 Biosynthesis

    • A. Ian Scott
    Pages 171-186

  16. Synthesis of Homochiral Pharmaceuticals using Effective Enantioselective Biocatalysts

    • H. J. Kooreman, J. H. G. M Mutsaers
    Pages 187-196

  17. Chemical Intervention in Catalysis by Enzymes

    • Colin J. Suckling
    Pages 197-205

  18. Immobilisation of Reductases by Two-Phase Systems and Polymer Matrices

    • G. L. Lemière, C. Gorrebeeck, M. Spanoghe, D. Lanens, R. A. Dommisse, J. A. Lepoivre et al.
    Pages 207-211

  19. Two Approaches in the Design of Plant Enzyme Inhibitors

    • Liliane Gorrichon
    Pages 213-223

  20. The Mechanism of the Urocanase Reaction

    • János Rétey
    Pages 225-231
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Keywords

About this book

In current thinking, Bioorganic Chemistry may be defined as the area of chemistry which lies in the border region between organic chemistry and biology and which describes and analyzes biological phenomena in terms of detailed molecular structures and molecular mechanisms. This molecular-level view of biological processes is not only essential to their fuller understanding but also serves as the platform for the application of the principles of such processes to areas of health­ care and technology. The objective of the ASI workshop on " Bioorganic Chemistry in Healthcare and Technology", held in the Hengelhoef Congress Centre in Houthalen-Helchteren, Belgium, from September 18-21, 1990, was to bring together most of the international experts in the field to discuss the current developments and new trends in bioorganic chemistry, especially in relation to the selected theme. The book presents nineteen invited plenary and session lectures and eighteen posters. These cover areas of (i) molecular design of therapeutic and agronomical agents based npon mechanistic rationale or drug-receptor interactions, (ii) production of substances of commercial value via combined organic chemical and bio-chemical methodologies, (iii) fundamental studies on the molecular mechanisms of enzymes and (iv) the evolution of conceptually new molecular systems which are programmed to execute specific recognition and/or catalytic functions. An abstracted version of the plenary discussion held at the end of the workshop is also included. We feel confident that the subject matter of this book will be of interest to a broad group of chemists engaged in academic or industrial research.

Editors and Affiliations

  • University of Amsterdam, Amsterdam, The Netherlands

    Upendra K. Pandit

  • University of Antwerp (RUCA), Antwerp, Belgium

    Frank C. Alderweireldt

Bibliographic Information

  • Book Title: Bioorganic Chemistry in Healthcare and Technology

  • Editors: Upendra K. Pandit, Frank C. Alderweireldt

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-1354-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1991

  • Softcover ISBN: 978-1-4684-1356-4Published: 18 February 2012

  • eBook ISBN: 978-1-4684-1354-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 326

  • Topics: Biochemistry, general, Physical Chemistry, Organic Chemistry

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