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Biological Responses in Cancer

  • Book
  • © 1985

Overview

Editors:
  1. Enrico Mihich

    1. Grace Cancer Drug Center, Roswell Park Memorial Institute, Buffalo, USA

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Angiogenesis, Tumor Vascularization, and Potential Interference with Tumor Growth

    • Pietro M. Gullino
    Pages 1-20

  3. Mechanisms of Tumor Invasion and Their Potential Therapeutic Modifications

    • Unnur P. Thorgeirsson, Taina Turpeenniemi-Hujanen, Lance A. Liotta
    Pages 21-46

  4. Mammary Tumor Growth Arrest by Collagen Synthesis Inhibitors

    • William R. Kidwell, Mozeena Bano, Susan J. Taylor
    Pages 47-69

  5. The Evolution of Phenotypic Diversity in Metastatic Tumor Cells

    • Garth L. Nicolson
    Pages 71-89

  6. Factors Influencing the Generation of Phenotypic Heterogeneity in Mammary Tumors

    • Untae Kim
    Pages 91-124

  7. The Mammary Gland

    • Barbara K. Vonderhaar, Maitreyi Bhattacharjee
    Pages 125-159

  8. Role of Cyclic AMP in Modifying the Growth of Mammary Carcinomas

    • Yoon Sang Cho-Chung, Freesia L. Huang, C. Lal Kapoor
    Pages 161-182

  9. Cellular Heterogeneity of Human Tumors

    • Harry K. Slocum, Gloria H. Heppner, Youcef M. Rustum
    Pages 183-248

  10. Back Matter

    Pages 249-256
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Keywords

About this book

The series of volumes entitled Biological Responses in Cancer provides information on approaches through which the interaction between neoplas­ tic and normal cells may be modified. Topics discussed in various volumes include immunological and host defense systems, control mechanisms of cell and population growth, cell differentiation, and cell transformation. This volume is specifically concerned with various aspects of cell interactions and regulation within heterogeneous tumor cell populations, and their role in tumor progression and metastasis. Knowledge in this area is likely to provide new leads toward the exploitation of novel cellular sites and mech­ anisms in the development of new types of therapies of cancer. Several topics are discussed within these general areas of consideration. The possibly unique characteristics and mechanisms of tumor vascularization and the potential sites of interference with angiogenesis that might have therapeutic impli­ cations are critically evaluated. Tumor cell-normal tissue interactions in­ volved in different phases of the growth and metastatic processes are dis­ cussed in two chapters dealing with mechanisms of tumor invasion and with the role of collagen in mammary tumor growth; here again potential leads are identified that may be exploited toward the development of new thera­ peutic approaches. The evolution of phenotypic diversity as a phenomenon complicating the biology of tumor metastasis and consequently affecting the opportunities offered by chemotherapy is also critically considered.

Editors and Affiliations

  • Grace Cancer Drug Center, Roswell Park Memorial Institute, Buffalo, USA

    Enrico Mihich

Bibliographic Information

  • Book Title: Biological Responses in Cancer

  • Editors: Enrico Mihich

  • DOI: https://doi.org/10.1007/978-1-4684-1236-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1985

  • Softcover ISBN: 978-1-4684-1238-3Published: 21 January 2013

  • eBook ISBN: 978-1-4684-1236-9Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XIII, 256

  • Number of Illustrations: 52 b/w illustrations

  • Topics: Oncology

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