Function and Metabolism of Phospholipids in the Central and Peripheral Nervous Systems

1. Front Matter

   Pages i-xi

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2. Structural Requirements for Phospholipids in Biological Membranes

   1. Front Matter

      Pages 1-1

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   2. Significance of Minor Glycerolipids in Membrane Structure and Function

      • Robert H. Michell, David Allan, J. B. Finean

      Pages 3-13

   3. Effect of P-Lipase C on the Structure and Function of Mitochondria and Sonic Fragments

      • G. F. Azzone, E. Viola, E. Strinna, M. Bragadin

      Pages 15-19

   4. Contribution of Phospholipids to the Surface Charge of Neuronal Membranes

      • W. J. Moore

      Pages 21-24

3. Metabolism and Turnover of Phospholipids in Nervous Tissue

   1. Front Matter

      Pages 25-25

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   2. Cytidine Diphosphate Diglyceride of Bovine Brain and Liver: Isolation and Characterization

      • W. Thompson

      Pages 27-36

   3. Synthesis and Turnover of Brain Phosphoglycerides — Results, Methods of Calculation and Interpretation

      • Lloyd A. Horrocks, Arrel D. Toews, Diann K. Thompson, Joseph Y. Chin

      Pages 37-54

   4. Metabolic Studies on 1-Alkyl- and 1-Alk-1′-Enyl-Glycerophosphat Ides in the Brain

      • H. Woelk, G. Porcellati, G. Goracci

      Pages 55-61

   5. The Contribution of Net Synthesis and Base-Exchange Reactions in Phospholipid Biosynthesis

      • G. Arienti, M. Brunetti, A. Gaiti, P. Orlando, G. Porcellati

      Pages 63-78

   6. Regulatory Aspects of Phospholipid Metabolism in Brain

      • P. Orlando, F. Cerrito, G. Porcellati

      Pages 79-94

   7. Renewal of Phospholipids in the Myelin Sheath

      • R. M. C. Dawson, R. M. Gould

      Pages 95-113

   8. Studies on Phospholipid Metabolism in Cultured Dissociated Brain Cells

      • Ephraim Yavin

      Pages 115-122

   9. The Turnover of Choline and Ethanolamine Plasmalogens in Glial and Neuronal Cells of the Rabbit in vivo

      • G. Goracci, E. Francescangeli, R. Mozzi, H. Woelk, G. Porcellati

      Pages 123-129

   10. Phospho- and Glycosphingolipid Metabolism in a Rat Neurinoma Clone (RN6) Studied in Tissue Culture

       • L. Binaglia, K. Karageosian, W. Stoffel

       Pages 131-137

   11. De novo Glycerolipid Biosynthesis in the Toad and Cattle Retina. Redirecting of the Pathway by Propranolol and Phentolamine

       • N. G. Bazán, M. G. Ilincheta de Boschero, N. M. Giusto, H. E. Pascual de Bazán

       Pages 139-148

   12. Accumulation and Metabolism of Phosphatidyl-CMP1 (CDP-Diglyceride) in the Pineal Gland of the Rat

       • George Hauser, Joseph Eichberg

       Pages 149-158

4. Aspects of Phospholipid Function in the Nervous System

   1. Front Matter

      Pages 159-159

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   2. The Role of Choline Kinase in the Brain

      • G. Brian Ansell, Sheila Spanner

      Pages 161-168

   3. Functional Roles of Phospholipids of Synaptosomal Membrane

      • Albert Y. Sun, Grace Y. Sun

      Pages 169-197

The present volume contains all the contributions and general discussion presented at the International Satellite Meeting on Func­ tion and Metabolism of Phospholipids in Central and Peripheral Nervous Systems held at Cortona, Tuscany, Italy in August 1975. The Satellite Meeting was organized on the frame of the 5th Inter­ national Congress of the International Society for Neurochemistry (Barcelona, 2-7 september 1975) and was just run before it. The publication of the scientific content of this volume has been made possible by the collaboration of the speakers, the discussants, the Meeting Chairman, the section chairmen and of all the scientists who have taken part at the Symposium and who deeply and actively discussed the lectures and the contributions to the General Discus­ sion which were delivered. In order to obtain rapid publication of the volume, however, the single discussions for each delivered contribution will not be reported here. The general subject of membrane structure, of the turnover of its lipid components in CNS and PNS, their functional implica­ tions and pharmacological actions, was explored in details from the stand-points of the various contributors in biophysics, biochem­ istry, physiology, cytology, pharmacology and pathology. The whole Symposium was effiCiently introduced and closed by Dr. W. Stoffel. The meeting has been thought to have been very successful.

• brain
• muscle
• myelin
• nervous system
• neurochemistry
• physiology

• University of Perugia, Perugia, Italy

  Giuseppe Porcellati

• Florence, Italy

  Luigi Amaducci

• University of Milan, Milan, Italy

  Claudio Galli

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