Endocrine and Biochemical Development of the Fetus and Neonate

1. Front Matter

   Pages i-ix

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2. Endocrine and Functional Aspects of Development

   1. Front Matter

      Pages 1-1

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   2. Endocrine Cytodifferentiation of the Rat Fetal Testis

      • Alfred Jost, Solange Magre

      Pages 3-10

   3. Transfer of Thyroid Hormones From the Mother to the Fetus

      • Gabriella Morreale de Escobar, Maria J. Obregón, Francisco Escobar del Rey

      Pages 11-25

   4. Neonatal Development of the Angiotensin Converting Enzyme. Effect of Hypothyroidism

      • Eugenio Jimenez, Maximiliano Ruiz, Mercedes Montiel

      Pages 27-31

   5. Development of the Pancreatic B-Cells: Growth Pattern and Functional Maturation

      • Bernard Portha

      Pages 33-43

   6. Insulin Receptor Binding Activity in Skeletal Muscle During Pregnancy

      • Marta Camps, Manuel Palacín, Xavier Testar, Antonio Zorzano

      Pages 45-50

   7. Insulin Binding and Receptor Tyrosine Kinase Activity in Rat Liver at Term Gestation

      • Carmen Martínez, Pilar Ruiz, Antonio Andrés, José M. Carrascosa

      Pages 51-54

   8. Glucose Homeostasis in Suckling Rats Undernourished During Intrauterine Life

      • Fernando Escrivá, Consuelo Rodríguez, Carmen Alvárez, Ana M. Pascual-Leone

      Pages 55-59

   9. Glucose Metabolism and Insulin Sensitivity During Suckling Period in Rats

      • Tarik Issad, Marçal Pastor-Anglada, Christine Coupé, Pascal Ferré, Jean Girard

      Pages 61-66

   10. Maturation of the Sympathetic Nervous System: Role in Neonatal Physiological Adaptations and in Cellular Development of Peripheral Tissues

       • Theodore A. Slotkin, Elizabeth M. Kudlacz, Qang-Chang Hou, Frederic J. Seidler

       Pages 67-75

   11. Effect of Thyroxine and Cortisol on Brain Catecholamines in Neonatal Rats

       • Luis Goya, Cecilia Aláez, Francisco Rivero, Maria J. Obregón, Ana M. Pascual-Leone

       Pages 77-81

   12. G-Proteins in Neonatal Liver: Ontogeny and Relationship to Activation of Adenylate Cyclase

       • Ifeanyi J. Arinze, Yumiko Kawai

       Pages 83-94

   13. Postnatal Development of β-Adrenergic Receptor Kinase Activity in Different Tissues of the Rat

       • Irene García-Higuera, Federico Mayor Jr.

       Pages 95-98

3. Molecular and Functional Aspects of Mitochondrial Development

   1. Front Matter

      Pages 99-99

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   2. Perinatal Development of Liver Mitochondrial Function

      • June R. Aprille

      Pages 101-112

   3. Postnatal Mitochondrial Differentiation in the Newborn Rat

      • José M. Cuezva, Carmen Valcarce, Ana M. Luis, José M. Izquierdo, Agustín Alconada, Margarita Chamorro

      Pages 113-135

   4. Uncoupling Protein mRNA Expression during the Perinatal Period of the Rat

      • Marta Giralt, Immaculada Martin, Roser Iglesias, Octavi Viñas, Teresa Mampel, Francesc Villarroya

      Pages 137-140

   5. Iodothyronine 5’-Deiodinase Activity in Brown Adipose Tissue during Perinatal Development

      • Marta Giralt, Octavi Viñas, Immaculada Martin, Louis Casteilla, Francesc Villarroya, Teresa Mampel et al.

      Pages 141-145

   6. Characterization of a System to Study the Uncoupling Protein Expression in Brown Adipocyte Primary Cultures

      • Almudena Porras, Matilde Peñas, Margarita Fernández, Manuel Benito

      Pages 147-152

The annual meeting of the Perinatal Biochemical Group of the Spanish Biochemical Society held in Madrid on December 15-16, 1989, provided an excellent opportunity to bring together a group of distinguished investigators both from Spain and from abroad with a common interest in developmental endocrinology and biochemistry. The aim of the symposium was to present and discuss the most recent developments in the areas of endocrine and biochemical processes critical to normal growth and maturation of the newborn. To achieve a high degree of interaction among the participants, subject reviews as well as short communications were include in the program. The reviews provided in-depth information on selected important topics. The purpose of short communications was two fold: (i) to provide a forum to discuss on-going investigations on related areas; and (ii) to present opportunities for active participation by young investigators. This format proved very successful in generating fruitful discussions among the participants. Taken together the review chapters and the short communications have resulted in a coherent and unified subject presentation. Advances in biochemistry, molecular biology and cell biology have provided not only new and exciting experimental approaches but also have opened up new directions in the investigation of differentiation and developmental processes at cellular, molecular and biochemical levels during the early stages of growth and maturation. In recent years a wealth of information in these areas of development has emerged at a rapid rate.

• Amino acid
• Lipid
• biochemistry
• development
• enzymes
• metabolism

• Universidad Autonoma de Madrid, Madrid, Spain

  José M. Cuezva

• C.S.I.C. Universidad Complutense de Madrid, Madrid, Spain

  Ana M. Pascual-Leone

• Case Western Reserve University, Cleveland, USA

  Mulchand S. Patel

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