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Explorations in Aging

  • Book
  • © 1975

Overview

Editors:
  1. Vincent J. Cristofalo

    1. Wistar Institute of Anatomy and Biology, Philadelphia, USA

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  2. Jay Roberts

    1. Medical College of Pennsylvania, Philadelphia, USA

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  3. Richard C. Adelman

    1. Fels Research Institute, Temple University School of Medicine, Philadelphia, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 61)

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Regulation of Cell Division in Aging Mouse Mammary Epithelium

    • Charles W. Daniel
    Pages 1-19

  3. Age Dependent Decline in Proliferation of Lymphocytes

    • Gordon Stoltzner, Takashi Makinodan
    Pages 21-37

  4. The Regulation of Cellular Aging by Nuclear Events in Cultured Normal Human Fibroblasts (WI-38)

    • Woodring E. Wright, Leonard Hayflick
    Pages 39-55

  5. Hydrocortisone as a Modulator of Cell Division and Population Life Span

    • Vincent J. Cristofalo
    Pages 57-79

  6. General Considerations of Membranes

    • E. J. Masoro
    Pages 81-94

  7. Function of Cardiac Muscle in Aging Rat

    • Myron L. Weisfeldt
    Pages 95-118

  8. Changes in Cardiac Membranes as a Function of Age with Particular Emphasis on Reactivity to Drugs

    • Jay Roberts, Paula B. Goldberg
    Pages 119-148

  9. Changes in Protein Synthesis in Heart

    • J. R. Florini, S. Geary, Y. Saito, E. J. Manowitz, R. S. Sorrentino
    Pages 149-162

  10. Senescence and Vascular Disease

    • George Martin, Charles Ogburn, Curtis Sprague
    Pages 163-193

  11. Changes in Hormone Binding and Responsiveness in Target Cells and Tissues During Aging

    • George S. Roth
    Pages 195-208

  12. Regulation of Corticosterone Levels and Liver Enzyme Activity in Aging Rats

    • Gary W. Britton, Samuel Rotenberg, Colette Freeman, Venera J. Britton, Karen Karoly, Louis Ceci et al.
    Pages 209-228

  13. Aging and the Regulation of Hormones: A View in October 1974

    • C. E. Finch
    Pages 229-238

  14. Aging and the Disposition of Glucose

    • Reubin Andres, Jordan D. Tobin
    Pages 239-249

  15. The Scientist and Social Policy on Aging

    • Elias S. Cohen
    Pages 251-261

  16. Cell Types Originating from Young and Old Mouse Kidney Explants

    • J. Lipetz, R. E. Boswell
    Pages 263-264

  17. Alterations in the Growth Rate and Glucose Metabolism of Chinese Hamster Cells in Vitro

    • J. M. Ryan, D. M. Pace
    Pages 265-265

  18. The Cristofalo Indices of Mutant Human Cells

    • R. A. Vincent Jr., P. C. Huang
    Pages 266-267

  19. Altered DNA Metabolism in Aged and Progeric Fibroblasts

    • J. R. Williams, J. B. Little, J. Epstein, W. Brown
    Pages 268-268

  20. The Survival of Haploid and Diploid Vertebrate Cells after Treatment with Mutagens

    • L. Mezger-Freed
    Pages 269-269
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Keywords

About this book

The three of us, working in different institutions but in the same city, were very aware of the differences between our diverse approaches to the biology of aging and our perceptions of the sub­ ject matter. However, three years ago we began to hold informal meetings to discuss our research. These meetings eventually be­ came more frequent and, with this association, we became increas­ ingly cognizant of the commonality of our research problems de­ spite our separate perspectives. The idea for this symposium, therefore, grew from our aware­ ness that the underlying problem of the biological basis for aging was a common denominator in our research. The papers presented here represent three areas of active investigation: cell divi­ sion, biological membranes and hormonal regulation. They are sub­ mitted with the expectations that a greater understanding of the role of each of these separate approaches will help clarify, not only the interrelationships between our fields of research, but more importantly, the biology of aging itself. ACKNOWLEDGEMENTS We would like to extend our sincere thanks for the interest and contributions of the companies listed below: Abbott Laboratories Hoffman-LaRoche Arthur D. Little McNeil Laboratories Bristol Laboratories Mead Johnson & Company Burroughs H'ellcome Co. Merck Sharp & Dohme Research Labs. Charles River Breeding Labs. Rom-Amer Pharmaceuticals Dow Chemical Co. Sandoz Pharmaceuticals E.R. Squibb & Sons, Inc. Schering Corp. Eli Lilly Research Laboratories Smith Kline Corp.

Editors and Affiliations

  • Wistar Institute of Anatomy and Biology, Philadelphia, USA

    Vincent J. Cristofalo

  • Medical College of Pennsylvania, Philadelphia, USA

    Jay Roberts

  • Fels Research Institute, Temple University School of Medicine, Philadelphia, USA

    Richard C. Adelman

Bibliographic Information

  • Book Title: Explorations in Aging

  • Editors: Vincent J. Cristofalo, Jay Roberts, Richard C. Adelman

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-9032-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1975

  • Softcover ISBN: 978-1-4615-9034-7Published: 20 June 2012

  • eBook ISBN: 978-1-4615-9032-3Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: IX, 307

  • Topics: Geriatrics/Gerontology

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