Skip to main content
SpringerLink
Log in
Book cover

Immunobiology of Proteins and Peptides · I

  • Book
  • © 1978

Overview

Editors:
  1. M. Z. Atassi

    1. Mayo Medical School, Rochester, USA
      University of Minnesota, Minneapolis, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. A. B. Stavitsky

    1. School of Medicine, Case Western Reserve University, Cleveland, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 98)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (29 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Antigenic Structure of Proteins

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Introduction

      • Elvin A. Kabat
      Pages 3-4

    3. Identifying Antigenic Determinants on Cytochrome c for B and T Cells

      • Morris Reichlin, Jerald Eng
      Pages 5-18

    4. First Consequences of the Determination of the Entire Antigenic Structure of Sperm-Whale Myoglobin

      • M. Zouhair Atassi, A. Latif Kazim
      Pages 19-40

    5. The Precise and Entire Antigenic Structure of Lysozyme: Implications of Surface-Simulation Synthesis and the Molecular Features of Protein Antigenic Sites

      • M. Zouhair Atassi
      Pages 41-99

    6. Immunochemistry of Bovine Serum Albumin

      • A. F. S. A. Habeeb
      Pages 101-117

    7. Analysis of a Complex Antigenic Site on Horse Cytochrome c

      • Ronald Jemmerson, E. Margoliash
      Pages 119-129

    8. A Model Implicating Altered Macrophage Function in H-2 Linked Nonresponsiveness to Hen Lysozyme

      • Alexander Miller
      Pages 131-139

  3. Immunobiology of Proteins and Peptides

    1. Front Matter

      Pages 141-141
      Download chapter PDF

    2. T-Lymphocyte Activation by Immunogenic Determinants

      • Joel W. Goodman, Sherman Fong, George K. Lewis, Roberta Kamin, Danute E. Nitecki, Georges Der Balian
      Pages 143-164

    3. Immunochemical Studies on the Tobacco Mosaic Virus Protein

      • Eli Benjamini, Cherry Y. Leung, Donna M. Rennick
      Pages 165-179

    4. Immunobiologic Properties of the Major Antigenic Determinants of the Ferredoxin Molecule

      • Barbara Kelly, Julia G. Levy
      Pages 181-198

    5. In Vitro Responses of Myoglobin-Primed Lymph Node Cells to Myoglobin and Myoglobin Synthetic Antigenic Peptides

      • A. B. Stavitsky, M. Z. Atassi, G. T. Gooch, G. L. Manderino, W. W. Harold, R. P. Pelley et al.
      Pages 199-223

    6. Genetic Control of the Antibody Response to Sperm Whale Myoglobin in Mice

      • Jay A. Berzofsky
      Pages 225-239

    7. Genetic Control of the Immune Response to Staphylococcal Nuclease in Mice

      • Jay A. Berzofsky, David S. Pisetsky, Ronald H. Schwartz, Alan N. Schechter, David H. Sachs
      Pages 241-257

    8. Peptides and Autoimmune Disease

      • E. H. Eylar
      Pages 259-281

    9. Mechanisms of Tolerance to HGG Induced in Neonatal and Adult Mice

      • D. C. Benjamin
      Pages 283-303

    10. Recognition of Lysozyme by Lymphocyte Subsets

      • Robert J. Scibienski, Vicki Klingmann, Cherry Leung, Karen Thompson, Eli Benjamini, Marc Feldmann
      Pages 305-321

  4. Immunobiology of Protein Conjugates

    1. Front Matter

      Pages 323-323
      Download chapter PDF
Back to top

Keywords

About this book

One of the central questions in immunology is the understanding in molecular terms of antigen-antibody interactions and of the cellu­ lar recognition of antigens. It is hoped that this understanding will extend eventually to the immunobiological basis of host defense to infectious agents and of tissue damage or deranged cell functions which stem from these reactions. A variety of natural and artificial substances have been used as models for these studies. Emphasis was placed upon substances of known and relatively uncomplicated chemical structures. These included polysaccharides, amino acid polymers, nu­ cleic acids and haptens. On the other hand. until recently there has been very little information on protein antigens. The complexity of these molecules posed an immense chemical obstacle to precise immuno­ chemical analysis. Indeed, it is this difficulty with proteins that spurred the synthesis and immunological studies of amino acid poly­ mers. The control and normal regulation of the immune system at the cellular-molecular interface and the great majority of antigens asso­ ciated with immune disorders are attributed to protein molecules. In the last few years great advances have been made in the analysis and synthesis of the antigenic sites of some proteins. The entire antigenic structures of myoglobin and lysozyme and the partial anti­ genic structures of several other proteins have been determined. Moreover, in the past seven years several biological responses resulting from the reactions of proteins and their peptides with cells of the immune system were described.

Editors and Affiliations

  • Mayo Medical School, Rochester, USA

    M. Z. Atassi

  • University of Minnesota, Minneapolis, USA

    M. Z. Atassi

  • School of Medicine, Case Western Reserve University, Cleveland, USA

    A. B. Stavitsky

Bibliographic Information

  • Book Title: Immunobiology of Proteins and Peptides · I

  • Editors: M. Z. Atassi, A. B. Stavitsky

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-8858-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4615-8860-3Published: 25 November 2012

  • eBook ISBN: 978-1-4615-8858-0Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 513

  • Topics: Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation