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  • © 1989

ADP-Ribose Transfer Reactions

Mechanisms and Biological Significance

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Table of contents (96 chapters)

  1. Front Matter

    Pages i-xvi
  2. Enzymology of ADP-Ribosylation

    1. Amino Acid-Specific ADP-Ribosylation: Purification and Properties of an Erythrocyte ADP-Ribosylarginine Hydrolase

      • Joel Moss, Su-Chen Tsai, Ronald Adamik, Hao-Chia Chen, Sally J. Stanley
      Pages 1-6
    2. Endogenous ADP-Ribosylation of Proteins at Cysteine Residues

      • Elaine L. Jacobson, Mingkwan Mingmuang, Nasreen Aboul-Ela, Myron K. Jacobson
      Pages 13-17
    3. Reversible ADP-Ribosylation of Dinitrogenase Reductase from Rhodospirillum rubrum Regulates the Activity of the Enzyme In Vivo and In Vitro

      • Paul W. Ludden, Scott A. Murrell, Robert G. Lowery, Wayne P. Fitzmaurice, Mark R. Pope, Leonard R. Saari et al.
      Pages 18-25
    4. In Vitro Evidence for Poly(ADP-Ribosyl)ation of DNA Polymerase α-Primase and Phosphorylation of Poly(ADP-Ribose) Synthetase by Protein Kinase C

      • Koichiro Yoshihara, Yasuharu Tanaka, Asako Itaya, Tomoya Kamiya, Takashi Hironaka, Takeyoshi Minaga et al.
      Pages 39-46
    5. Poly(ADP-Ribose) Glycohydrolase and ADP-Ribosyl Group Turnover

      • Kazuyuki Hatakeyama, Yasuo Nemoto, Kunihiro Ueda, Osamu Hayaishi
      Pages 47-52
    6. In Vitro ADP-Ribosylation Utilizing 2′Deoxy-NAD+ as a Substrate

      • Rafael Alvarez-Gonzalez, Joel Moss, Claude Niedergang, Felix R. Althaus
      Pages 53-56
    7. Reconstitution of an In Vitro Poly(ADP-Ribose) Turnover System

      • Luc Menard, Louis Thibault, Alain Gaudreau, Guy G. Poirier
      Pages 57-61
    8. Biosynthesis and Degradation of Poly(ADP-Ribose) Synthetase

      • Isamu Kameshita, Yasuhiro Mitsuuchi, Michiko Matsuda, Yutaka Shizuta
      Pages 71-75
    9. Monoclonal Antibodies Against Poly(ADP-Ribose) Polymerase: Epitope Mapping, Inhibition of Activity and Interspecies Immunoreactivity

      • Daniel Lamarre, Gilbert de Murcia, Brian Talbot, Claude Laplante, Yvan Leduc, Guy Poirier
      Pages 76-80
    10. Localization of the Zinc-Binding Sites in the DNA-Binding Domain of the Bovine Poly(ADP-Ribose) Polymerase

      • Alice Mazen, Daniel Lamarre, Guy Poirier, Gérard Gradwohl, Gilbert de Murcia
      Pages 89-93
    11. Heterogeneity of Polyclonal Antisera to ADP-Ribose and Their Use as Probes for ADP-Ribosylation in Human Tumor Cells

      • Sarada C. Prasad, Peter J. Thraves, Jane Boyle, Anatoly Dritschilo
      Pages 94-100
    12. ADP-Ribosylating Activity in Sulfolobus solfataricus

      • Piera Quesada, Maria Rosaria Faraone-Mennella, Mario De Rosa, Agata Gambacorta, Barbara Nicolaus, Benedetta Farina
      Pages 101-104

About this book

Current interest in NAD (Nicotinamide adenine dinucleotide) in biological systems focuses on its role in ADP-ribose transfer reactions. These appear to be fundamentally involved in the regulation of many physiological processes. The contributions in this monograph thus represent the range of research in the very active investigation of niacin metabolism. The major topics covered are: ??? - Enzymology of ADP-Ribosylation - ADP-Ribosylation and Chromatin Function - Carcinogenesis and Differentiation - NAD Metabolism and Chemotherapy - ADP-Ribosylation and Signal Transduction - Molecular Genetic Approaches to ADP-Ribosylation

Editors and Affiliations

  • Department of Biochemistry, Texas College of Osteopathic Medicine, Fort Worth, USA

    Myron K. Jacobson

  • Department of Medicine, Texas College of Osteopathic Medicine, Fort Worth, USA

    Elaine L. Jacobson

Bibliographic Information

  • Book Title: ADP-Ribose Transfer Reactions

  • Book Subtitle: Mechanisms and Biological Significance

  • Editors: Myron K. Jacobson, Elaine L. Jacobson

  • DOI: https://doi.org/10.1007/978-1-4615-8507-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1989

  • Softcover ISBN: 978-1-4615-8509-1Published: 11 January 2012

  • eBook ISBN: 978-1-4615-8507-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 527

  • Topics: Biochemistry, general

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access