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The Herpesviruses

Immunobiology and Prophylaxis of Human Herpesvirus Infections

  • Book
  • © 1985

Overview

Editors:
  1. Bernard Roizman

    1. University of Chicago, Chicago, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Carlos Lopez

    1. Sloan-Kettering Institute for Cancer Research, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: The Viruses (VIRS)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xviii
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  2. The Natural History of Genital Herpes Simplex Virus

    • Lawrence Corey
    Pages 1-35

  3. Natural Resistance Mechanisms in Herpes Simplex Virus Infections

    • Carlos Lopez
    Pages 37-68

  4. Humoral Response to Herpes Simplex Virus Infections

    • Bodil Norrild
    Pages 69-86

  5. The T-Cell-Mediated Immune Response of Mice to Herpes Simplex Virus

    • A. A. Nash, K.-N. Leung, P. Wildy
    Pages 87-102

  6. Immunopathology of Herpesvirus Infections

    • Barry T. Rouse
    Pages 103-119

  7. Cell-Mediated Immunity in Cytomegalovirus Infections

    • Gerald V. Quinnan Jr.
    Pages 121-145

  8. In Vivo Studies of Epstein-Barr Virus and Other Lymphotropic Herpesviruses of Primates

    • Harvey Rabin
    Pages 147-170

  9. Cell-Mediated Immunity to EBV

    • Eva Klein
    Pages 171-182

  10. Immunobiology of EBV-Associated Cancers

    • Gary R. Pearson
    Pages 183-199

  11. Cytomegalovirus Infection after Organ Allografting

    • Joel D. Meyers
    Pages 201-227

  12. Epstein-Barr Virus and the X- Linked Lymphoproliferative Syndrome

    • John L. Sullivan
    Pages 229-250

  13. Abnormal Responses to EBV Infection in Patients with Impairment of the Interferon System

    • Jean-Louis Virelizier
    Pages 251-264

  14. Vaccination against Herpes Simplex Virus Infections

    • Bernard Meignier
    Pages 265-296

  15. CMV Vaccines

    • Stanley A. Plotkin
    Pages 297-312

  16. Live Attenuated Varicella Vaccine

    • Anne A. Gershon
    Pages 313-326

  17. A Subunit Vaccine against Epstein-Barr Virus

    • M. A. Epstein
    Pages 327-337

  18. A Perspective on the Therapy of Human Herpesvirus Infections

    • Richard J. Whitley
    Pages 339-369

  19. The Role of Interferon in Immunity and Prophylaxis

    • François Lebel, Martin S. Hirsch
    Pages 371-393

  20. Effects of Immunopotentiating and Immunomodulating Agents on Experimental and Clinical Herpesvirus Infections

    • Georges H. Werner, Aurelio Zerial
    Pages 395-416
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Keywords

About this book

'You damn sadist/said mr cummings 'you try to make people think. ' -Ezra Pound (Canto 89) What makes herpesviruses unique? It is certainly not the size of their genomes or the individual features of their reproductive cycle, although in toto striking features that are exclusive to the herpesviruses abound. Unquestionably, the pre-eminent feature is the relationship of herpes­ viruses with their natural hosts. As described in preceding volumes, all herpesviruses seem to be able to colonize and to remain in a latent, nonproductive form for life of their hosts. Once established in the host, the relationship is best described as that of an armed truce. What happens when this truce breaks down or when the host encounters the virus for the first time is the subject of this volume. We have focused primarily on the five human herpesviruses [herpes simplex virus 1 (HSV-l), herpes simplex virus 2 (HSV-2), cytomegalovirus (CMV), varicella zoster virus (VZV) and Epstein-Barr virus (EBV)] because much more is known about them than about any other herpesviruses, and because it is of interest to compare both the diversity of manifestations of infections with human herpesviruses and the spectrum of human responses to these viruses. This volume summarizes the current knowledge of the pathogenesis and immunobiology of herpesvirus infections in man and describes new and developing approaches to prophylaxis and treatment. It contains con­ tributions from distinguished research scientists presently engaged at the forefront of these scientific investigations.

Editors and Affiliations

  • University of Chicago, Chicago, USA

    Bernard Roizman

  • Sloan-Kettering Institute for Cancer Research, New York, USA

    Carlos Lopez

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