Subcellular Biochemistry

1. Front Matter

   Pages i-xviii

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2. Structures, Properties, and Possible Biologic Functions of Polyadenylic Acid

   • Timothy P. Karpetsky, Mark S. Boguski, Carl C. Levy

   Pages 1-116

3. Computer Simulation of Density-Gradient Centrifugation

   • Jens Steensgaard, Niels Peter Hundahl Møller

   Pages 117-141

4. Crown-Gall and Agrobacterium tumefaciens: Survey of a Plant-Cell-Transformation System of Interest to Medicine and Agriculture

   • U. C. Knopf

   Pages 143-173

5. The Petite Mutation in Yeast

   • Peter A. Whittaker

   Pages 175-232

6. The Role of Lipids in the Structure and Function of Membranes

   • Giorgio Lenaz

   Pages 233-343

7. Dehydrogenases of the Plasma Membrane

   • Frederick L. Crane, Hans Goldenberg, D. James Morré, Hans Löw

   Pages 345-399

8. Transport Processes in Membranes: A Consideration of Membrane Potential across Thick and Thin Membranes

   • N. Lakshminarayanaiah

   Pages 401-494

9. Back Matter

   Pages 495-526

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This volume continues the tradition of SUBCELLULAR BIOCHEMISTRY of trying to break down interdisciplinary barriers in the study of cell function and of bringing the reader's attention to less well studied, but nevertheless useful, biological systems. We start with an extensive article by T. P. Karpetsky, M. S. Boguski and C. C. Levy on the structure, properties and possible functions of polyadenylic acid. Apart from revealing a general lack of appreciation of many important aspects of the chemical properties of poly adenylic acid, the literature also shows that there is a great gulf between those who study the biological role of polyadenylic acid. and those who study its physicochemi­ cal properties. The article by Karpetsky and his colleagues is an attempt to overcome this lack of communication and to present an integrated view of the subject. The authors go into the subject in full detail and the more biologically inclined reader may on occasion have to reread his nucleic acid physical chemistry notes! However, the effort is worthwhile and the article is a timely reminder that we cannot treat nucleic acids as mere abstractions, but that they are complex organic macromolecules capable of equally complex, but nevertheless important, interactions. The next article is by J. Steensgaard and N. P. Hundahl M0ller and deals with computer simulation of density gradient centrifugation systems.

• Coenzym
• DNA
• Nucleotide
• RNA
• amino acid
• biochemistry
• biology
• chemistry
• enzyme
• enzymes
• mitochondria
• mutation
• nucleic acid
• polysaccharide
• protein synthesis

• University College London, London, England

  Donald B. Roodyn

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