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Psychopharmacogenetics

  • Book
  • © 1975

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Editors:
  1. Basil E. Eleftheriou

    1. The Jackson Laboratory, Bar Harbor, USA

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Table of contents (15 chapters)

  1. Front Matter

    Pages ii-viii
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  2. Psychopharmacogenetics: An Integrative Approach to the Study of Genes, Drugs and Behavior

    • Basil E. Eleftheriou
    Pages 1-10

  3. Genes and Drugs as Behavior Modifying Agents

    • John L. Fuller, Carole D. Hansult
    Pages 11-18

  4. Effects of Apomorphine in Mice of Different Strains

    • I. P. Lapin
    Pages 19-32

  5. Implications of Psychopharmacogenetics Research

    • W. Kalow, A. E. LeBlanc
    Pages 33-42

  6. Recombinant Inbred Strains: A Novel Genetic Approach for Psychopharmacogeneticists

    • Basil E. Eleftheriou, Penelope K. Elias
    Pages 43-71

  7. Genetic Analysis of Morphine Effects: Activity, Analgesia, Tolerance and Sensitization

    • Louis Shuster
    Pages 73-97

  8. Exploratory Activity: Genetic Analysis of its Modification by Various Pharmacologic Agents

    • Alberto Oliverio, Claudio Castellano
    Pages 99-126

  9. Alcohol Imbibition and Behavior: A Comparative Genetic Approach

    • Kalervo Eriksson
    Pages 127-168

  10. Neuroleptic-Induced Movement Disorders: Pharmacology and Treatment

    • William E. Fann, John L. Sullivan III, C. Raymond Lake, Robert D. Miller
    Pages 169-182

  11. Pharmacogenetics: Clinical and Experimental Studies in Man

    • Gilbert S. Omenn, A. G. Motulsky
    Pages 183-228

  12. The Role of Genotype in Behavioral Responses to Anesthetics

    • Merrill F. Elias, Clyde A. Pentz
    Pages 229-321

  13. Species Differences in Response to Amphetamine

    • Everett H. Ellinwood Jr, M. Marlyne Kilbey
    Pages 323-375

  14. Some Drug-Drug Interactions Involving Psychotropic Agents

    • William E. Fann, Bruce W. Richman
    Pages 377-382

  15. Audiogenic Seizures and Acoustic Priming

    • Kurt Schlesinger, Seth K. Sharpless
    Pages 383-433

  16. Potential Applications of Multivariate Analysis of Variance to Psychopharmacogenetic Research

    • Merrill F. Elias
    Pages 435-465

  17. Back Matter

    Pages 467-472
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Keywords

About this book

This short volume of an apparently double hybrid science deals with major pharmacologic effects on behavior in genetically defined animal and, to a lesser extent, human populations. Thus, a new name, psychopharmacogenetics, was coined to designate its contents. The necessity for such compilation of some of the major data has become increasingly urgent. For some time now, there has been available information dealing with pharmacogenetics and behavior genetics. Recently, with ever-increasing frequency, however, data have been accumulating that deal with the effects of specific drugs on behavior and behavioral responses in animals with known genetic background. Initially, the data were gathered in various species and in a number of strains within given species of animals. With the availability of mutations, inbred strains, segregating strains of various types, recombinant inbred strains and congenic lines, the experimental approach to psychopharmacogenetics has now reached a new peak of sophistication. This volume attempts to present some of the major experiments in this area, along with comprehensive sur­ vey of the status of a given drug. It is hoped that reading of the information that has been com­ piled herein will ultimately lead to a stimulus for further research in the areas outlined, as well as make the reader acquainted with new approaches to drug:behavior:genetic research. Basil E. Eleftheriou June, 1975 v CONTENTS Introduction. • • • • • • . . . . . . . . . . . . . . . 1 Basil E. Eleftheriou Genes and Drugs as Behavior Modifying Agents.

Editors and Affiliations

  • The Jackson Laboratory, Bar Harbor, USA

    Basil E. Eleftheriou

Bibliographic Information

  • Book Title: Psychopharmacogenetics

  • Editors: Basil E. Eleftheriou

  • DOI: https://doi.org/10.1007/978-1-4615-7697-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1975

  • Softcover ISBN: 978-1-4615-7699-0Published: 29 April 2012

  • eBook ISBN: 978-1-4615-7697-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 472

  • Topics: Clinical Psychology, Psychopharmacology

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