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Clinical Approach to Infection in the Compromised Host

  • Book
  • © 1988

Overview

Editors:
  1. Robert H. Rubin

    1. Infectious Disease and Transplantation Units, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, USA

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  2. Lowell S. Young

    1. Kuzell Institute for Arthritis and Infectious Diseases, Division of Infectious Diseases, Pacific Presbyterian Medical Center, San Francisco, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xxix
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  2. Introduction

    • Lowell S. Young, Robert H. Rubin
    Pages 1-4

  3. Epidemiology and Prevention of Infection in the Compromised Host

    • James C. Wade, Stephen C. Schimpff
    Pages 5-40

  4. Defects in Host-Defense Mechanisms

    • Jos W. M. van der Meer
    Pages 41-73

  5. Fever and Septicemia

    • Lowell S. Young
    Pages 75-114

  6. Dermatologic Manifestations of Infection in the Compromised Host

    • John S. Wolfson, Arthur J. Sober
    Pages 115-130

  7. Etiology and Management of the Compromised Patient with Fever and Pulmonary Infiltrates

    • Robert H. Rubin, Reginald Greene
    Pages 131-163

  8. Central Nervous System Infections in the Compromised Host

    • Donald Armstrong, Bruce Polsky
    Pages 165-191

  9. Fungal Infections in the Compromised Host

    • Françoise Meunier
    Pages 193-220

  10. Mycobacterial and Nocardial Infections in the Compromised Host

    • Harvey B. Simon
    Pages 221-251

  11. Parasitic Diseases in the Compromised Host

    • Joel Ruskin
    Pages 253-304

  12. Legionellosis in the Compromised Host

    • Neil M. Ampel, Edward J. Wing
    Pages 305-324

  13. Viral Hepatitis in the Compromised Host

    • Jules L. Dienstag
    Pages 325-345

  14. Herpes Group Virus Infections in the Compromised Host

    • Martin S. Hirsch
    Pages 347-366

  15. Morbidity in Compromised Patients due to Viruses other than Herpes Group and Hepatitis Viruses

    • Robert T. Schooley
    Pages 367-380

  16. Acquired Immunodeficiency Syndrome

    • Michael S. Gottlieb
    Pages 381-405

  17. Infections Complicating Congenital Immunodeficiency Syndromes

    • Harry R. Hill
    Pages 407-438

  18. Diagnosis and Management of Infectious Disease Problems in the Child with Malignant Disease

    • Philip A. Pizzo
    Pages 439-466

  19. Management of Infections in Leukemia and Lymphoma

    • Lowell S. Young
    Pages 467-501

  20. Evaluation and Management of Infections in Patients with Collagen Vascular Disease

    • Donald G. Payan
    Pages 503-524
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Keywords

About this book

"Infection in the Compromised Host" has become a classic chapter in textbooks devoted to infectious diseases and internal medicine. The numbers of compromised hosts are increasing in the era of modem medicine because of our expanded capabilities to deal with difficult diseases, especially neoplasms. As a consequence, microbiologic complications related to the intensive care administered to these patients are increasing as well. Under these circum­ stances, not only does the underlying illness create conditions favorable for the development of unusual infections, but often the therapy contributes to the acquisition of potential pathogens that turn into agents responsible for severe and frequently fatal disease. Granulocytopenia and immunosuppression have been the two key fac tors in predisposing patients with cancer and other serious diseases to severe bacterial infections. Colonization by hospital-acquired pathogens and breaks in the anatomic barriers-as a result of disease or medical intervention-have contributed to the high incidence of infectious diseases in these patients. Although there is some overlap between the types of infection in granulocytopenic and immunosuppressed hosts, each ofthese clinical entities has distinctive features thatjustify considering them separately, reserving the term immunocompromised hosts only when refer­ ring to patients who are predisposed to opportunistic infections. For about two decades, infections in granulocytopenic patients have attracted the atten­ tion of clinicians because they represent a model for the study of antimicrobial drugs in hosts deprived of an essential element of defense against bacterial infection, that is, an adequate number of normally functioning granulocytes.

Editors and Affiliations

  • Infectious Disease and Transplantation Units, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, USA

    Robert H. Rubin

  • Kuzell Institute for Arthritis and Infectious Diseases, Division of Infectious Diseases, Pacific Presbyterian Medical Center, San Francisco, USA

    Lowell S. Young

Bibliographic Information

  • Book Title: Clinical Approach to Infection in the Compromised Host

  • Editors: Robert H. Rubin, Lowell S. Young

  • DOI: https://doi.org/10.1007/978-1-4615-6645-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1988

  • Softcover ISBN: 978-1-4615-6647-2Published: 22 December 2012

  • eBook ISBN: 978-1-4615-6645-8Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XXIX, 685

  • Number of Illustrations: 88 b/w illustrations

  • Topics: Internal Medicine

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