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Table of contents (27 chapters)
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Front Matter
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Basis of the concept
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Front Matter
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Restenosis and remodeling: the facts
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Front Matter
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Restenosis and remodeling: the targets revisited
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Front Matter
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Molecular aspects of remodeling
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Front Matter
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About this book
There is a desperate need to heighten understanding of the remodeling process at the molecular, cellular, and arterial level. Vascular remodeling is a well established concept in the field of atherosclerosis and hypertension, but only in recent years has its applicability to the field of restenosis become pivotal. Accordingly, the editors perceived the need to assemble the first book dedicated to the concept of coronary artery remodeling in restenosis, in order to clearly review the experiments leading to the remodeling hypothesis and integrate this with the neointimal hyperplasia (tumor) model for the development of the restenotic lesion.
The authors of this book present their experience to facilitate the understanding of the mechanisms for coronary restenosis and remodeling. The various experimental models, clinical issues, and basic mechanisms are reviewed in detail, resulting in a fresh approach to a vexing clinical problem. Arterial Remodeling: A Critical Factor in Restenosis will be useful to the physician and trainee who have an interest in restenosis, and specifically in the major pathophysiologic process which determines the fate of arterial healing in patients following percutaneous coronary revascularization. It is hoped that this book will lay the foundation for more effective therapies that will reduce the chance of constrictive remodeling and improve the long-term efficacy of non-surgical coronary revascularization in the future.
Editors and Affiliations
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Necker University, Paris, France
Antoine Lafont
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Cleveland Clinic Foundation, Cleveland, USA
Eric J. Topol
Bibliographic Information
Book Title: Arterial Remodeling: A Critical Factor in Restenosis
Editors: Antoine Lafont, Eric J. Topol
Series Title: Developments in Cardiovascular Medicine
DOI: https://doi.org/10.1007/978-1-4615-6079-1
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1997
Hardcover ISBN: 978-0-7923-8008-5Published: 31 October 1997
Softcover ISBN: 978-1-4613-7785-6Published: 11 October 2012
eBook ISBN: 978-1-4615-6079-1Published: 06 December 2012
Series ISSN: 0166-9842
Edition Number: 1
Number of Pages: XXIX, 569
Topics: Cardiology