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Oxidative Stress and Signal Transduction

  • Book
  • © 1997

Overview

Editors:
  1. Henry Jay Forman

    1. University of Southern California, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Enrique Cadenas

    1. University of Southern California, USA

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xv
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  2. Immediate Cellular Responses to Oxidative Stress and the Production of Second Messengers

    1. Front Matter

      Pages 1-1
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    2. Activation and Regulation of the Nitric Oxide-Cyclic GMP Signal Transduction Pathway by Oxidative Stress

      • Louis J. Ignarro
      Pages 3-31

    3. Peroxynitrite and Cell Signaling

      • Nathan Spear, Alvaro G. Estévez, Rafael Radi, Joseph S. Beckman
      Pages 32-51

    4. Nitric Oxide Signaling Through Mitochondrial Calcium Release

      • Christoph Richter, Renato Laffranchi
      Pages 52-76

    5. Phospholipase A2 Activation: An Early Manifestation of Oxidative Stress

      • Alex Sevanian, Julia Rashba-Step
      Pages 77-107

    6. Oxidant-Mediated Activation of Phospholipases C and D

      • Viswanathan Natarajan, William M. Scribner, Suryanarayana Vepa
      Pages 108-133

    7. Peroxide Tone in Eicosanoid Signaling

      • Richard J. Kulmacz, William E. M. Lands
      Pages 134-156

    8. Protein Kinase C as a Sensor for Oxidative Stress in Tumor Promotion and Chemoprevention

      • Rayudu Gopalakrishna, Zhen-Hai Chen, Usha Gundimeda
      Pages 157-180

    9. Tyrosine Phosphorylation in Oxidative Stress

      • Gary L. Schieven
      Pages 181-199

    10. Reactive Oxygen Intermediates as Signaling Molecules Regulating Leukocyte Activation

      • Léa Fialkow, Gregory P. Downey
      Pages 200-235

  3. The Connection of Oxidative Induced Changes in Second Messengers and Transcription Factors with Activation of Gene Expression

    1. Front Matter

      Pages 237-237
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    2. Reactive Oxygen Intermediates as Primary Signals and Second Messengers in the Activation of Transcription Factors

      • Klaus Schulze-Osthoff, Manuel Bauer, Markus Vogt, Sebastian Wesselborg, Patrick A. Baeuerle
      Pages 239-259

    3. STAT Activation by Oxidative Stress

      • Amy R. Simon, Barry L. Fanburg, Brent H. Cochran
      Pages 260-271

    4. The Antioxidant Response Element

      • Leonard V. Favreau, Cecil B. Pickett
      Pages 272-288

    5. Oxyradicals as Signal Transducers

      • Roy H. Burdon
      Pages 289-319

  4. Gene Expression in Response to Oxidative Stress

    1. Front Matter

      Pages 321-321
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    2. Modulation by Oxidants and Antioxidants of Signal Transduction and Smooth Muscle Cell Proliferation

      • Angelo Azzi, Daniel Boscoboinik, Orazio Cantoni, Agata Fazzio, Dominique Marilley, Valerie O’Donnell et al.
      Pages 323-342

    3. The Role of Heme Oxygenase-1 in the Mammalian Stress Response: Molecular Aspects of Regulation and Function

      • Stefan W. Ryter, Rex M. Tyrrell
      Pages 343-386

    4. Induction of Gene Expression by Environmental Oxidants Associated with Inflammation, Fibrogenesis, and Carcinogenesis

      • Yvonne M. W. Janssen, Cynthia R. Timblin, Christine L. Zanella, L. Albert Jimenez, Brooke T. Mossman
      Pages 387-414
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Keywords

About this book

In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene.

Editors and Affiliations

  • University of Southern California, USA

    Henry Jay Forman, Enrique Cadenas

Bibliographic Information

  • Book Title: Oxidative Stress and Signal Transduction

  • Editors: Henry Jay Forman, Enrique Cadenas

  • DOI: https://doi.org/10.1007/978-1-4615-5981-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Hardcover ISBN: 978-0-412-07681-7Published: 31 July 1997

  • Softcover ISBN: 978-1-4613-7741-2Published: 27 September 2012

  • eBook ISBN: 978-1-4615-5981-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XV, 475

  • Topics: Biochemistry, general, Pharmacology/Toxicology, Animal Physiology

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