Neurobiology

1. Front Matter

   Pages i-ix

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2. Ionic Channels

   1. The Role of the N-Terminal of the cGMP-Gated Channel from Vertebrate Rods

      • G. Bucossi, M. Nizzari, V. Torre

      Pages 1-9

   2. Electrophysiological Studies of Mitochondrial Channels

      • Maria Luisa Campo, Concepción Muro, Henry Tedeschi, Kathleen W. Kinnally

      Pages 11-21

   3. Functional and Structural Constituents of Neuronal Ca2+ Channel Modulation by Neurotransmitters

      • E. Carbone, V. Magnelli, V. Carabelli, D. Platano, G. Aicardi

      Pages 23-40

   4. Functional, Conformational, and Molecular Modelling Studies of Voltage-Sensitivity and Selectivity of Synthetic Peptides Derived from Ion Channels

      • Pascal Cosette, Olivier Helluin, Jason Breed, Yehonathan Pouny, Yechiel Shai, Mark S. P. Sansom et al.

      Pages 41-62

   5. The Hyperpolarization-Activated Current (Ih/Iq) in Rat Hippocampal Neurons

      • S. Gasparini, G. Maccaferri, R. D’Ambrosio, D. DiFrancesco

      Pages 63-74

   6. Properties of Native and Cloned Cyclic Nucleotide Gated Channels from Bovine

      • Paola Gavazzo, Cristiana Picco, Letizia Maxia, Anna Menini

      Pages 75-83

   7. NMDA-Induced Motor Activation in Rodents

      • Lydia Giménez-Llort, Sergi Ferré, Emili Martínez

      Pages 85-94

   8. Target Striatal Cells Regulate Development of Midbrain Dopaminergic Neurones

      • Carla Perrone-Capano, Giuseppina Amadoro, Angela Tino, Roberto Pernas-Alonso, Bruno Esposito, Umberto di Porzio

      Pages 95-107

   9. Comparison of “Near Membrane” and Bulk Cytoplasmic Calcium Concentration in Single Cardiac Ventricular Myocytes During Spontaneous Calcium Waves

      • A. W. Trafford, M. E. Díaz, S. C. O’Neill, D. A. Eisner

      Pages 109-128

3. Sensory Transduction

   1. Facts and Fantasies about Hair Cells

      • Jonathan F. Ashmore

      Pages 129-137

   2. Precise and Perceptually Relevant Processing of Amplitude Modulation in the Auditory System

      • Frédéric Berthommier, Christian Lorenzi

      Pages 139-153

   3. Olfactory Sensory Transduction

      • Marie-Christine Broillet, Stuart Firestein

      Pages 155-164

   4. The Vomeronasal Organ

      • A. Cavaggioni, Carla Mucignat-Caretta, G. Sartor, R. Tirindelli

      Pages 165-173

   5. Neurogenic Inflammation of the Skin Induces Plastic Changes in α2-Adrenergic Pain Modulation in Rats

      • Heikki Mansikka, Antti Pertovaara

      Pages 175-182

   6. Role of K+ Channels in Semicircular Canal Adaptation

      • Paola Perin, Sergio Masetto

      Pages 183-191

   7. Potassium Currents of Hair Cells in Thin Slices of Vestibular Epithelium

      • Ivo Prigioni, Giancarlo Russo, Walter Marcotti

      Pages 193-200

   8. A Compartment Model for Vertebrate Phototransduction Predicts Sensitivity and Adaptation

      • Jean-Pierre Raynauld

      Pages 201-215

   9. Modelling Odor Intensity and Odor Quality Coding in Olfactory Systems

      • Jean-Pierre Rospars, Petr Lánskỳ, Jean-Claude Fort

      Pages 217-231

   10. The Electronic Ear

       • André van Schaik, Ray Meddis

       Pages 233-250

Understanding how the brain works is undoubtedly the greatest challenge for human intelligence and one of the most ambitious goals of contemporary science. We are certainly far from this goal, but significant advancements in several fields of Neuroscience and Neurobiology are being obtained at an increasing pace. The NATO ASI School in Neurobiology, held in Erice May 2-12,1995, as the 23rd Course of the International School of Biophysics, provided an update on three basic topics: Biophysics and Molecular Biology ofIon Channels, Sensory Transduction, and Higher Order Functions. Current knowledge on these subjects was covered by formal lectures and critical discussions between lecturers and participants. This book collects original contributions from those scientists who attended the School. Many students presented their results in poster sessions, steering lively informal discussions. A selection of these contributions is also included. A major portion of the program of the School was devoted to a general overview of current trends of thought and experimental approaches in neurobiology, emphasising the importance of understanding molecular aspects of the elementary events underlying sensory transduction and processing in the nervous system, without indulging however in a pure reductionistic view of such complex phenomena. Recent studies of molecular biology and the electrophysiology of heterologously expressed ionic channels, have shed new light on the molecular mechanisms underlying ionic permeation of excitable membranes and its regulation by physical and chemical parameters.

• Nervous System
• anatomy
• biophysics
• neurobiology
• neurons
• neuroscience
• physiology

• Università di Genova, Genova, Italy

  Vincent Torre

• Consiglio Nazionale delle Richerche (CNR), Genova, Italy

  Franco Conti

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