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Chemistry and Biology of Serpins

  • Book
  • © 1997

Overview

Editors:
  1. Frank C. Church

    1. University of North Carolina School of Medicine, Chapel Hill, USA

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  2. Dennis D. Cunningham

    1. University of California, Irvine, USA

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  3. David Ginsburg

    1. Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, USA

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  4. Maureane Hoffman

    1. Duke University and Durham VA Medical Centers, Durham, USA

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  5. Stuart R. Stone

    1. Late of Monash University, Clayton, Australia

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  6. Douglas M. Tollefsen

    1. Washington University School of Medicine, St. Louis, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 425)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xix
    Download chapter PDF

  2. Introduction

    1. Serpins

      • James Travis
      Pages 1-4

    2. Serpins

      • Stuart R. Stone, James C. Whisstock, Stephen P. Bottomley, Paul C. R. Hopkins
      Pages 5-15

  3. Coagulation

    1. Antithrombin

      • Ingemar Björk, Steven T. Olson
      Pages 17-33

    2. Heparin Cofactor II

      • Douglas M. Tollefsen
      Pages 35-44

    3. PCI: Protein C Inhibitor?

      • Scott T. Cooper, Frank C. Church
      Pages 45-54

    4. Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes

      • Debra L. Becker, Jim C. Fredenburgh, Alan R. Stafford, Jeffrey I. Weitz
      Pages 55-66

  4. Neurobiology and Cancer

    1. Regulation of Neurons and Astrocytes by Thrombin and Protease Nexin-1

      • Dennis D. Cunningham, Frances M. Donovan
      Pages 67-75

    2. Maspin

      • R. Sager, S. Sheng, P. Pemberton, M. J. C. Hendrix
      Pages 77-88

    3. Proteases and Protease Inhibitors in Tumor Progression

      • Yves A. DeClerck, Suzan Imren, Anthony M. P. Montgomery, Barbara M. Mueller, Ralph A. Reisfeld, Walter E. Laug
      Pages 89-97

  5. Fibrinolysis

    1. The Role of Reactive-Center Loop Mobility in the Serpin Inhibitory Mechanism

      • Daniel A. Lawrence
      Pages 99-108

    2. Substrate Specificity of Tissue Type Plasminogen Activator

      • Edwin L. Madison
      Pages 109-121

    3. Plasminogen Activator Inhibitor Type-2

      • Tor Ny, Peter Mikus
      Pages 123-130

    4. Of Mice and Men

      • Daniel T. Eitzman, David Ginsburg
      Pages 131-141

  6. Development and Reproduction

    1. Biology of Progesterone-Induced Uterine Serpins

      • Peter J. Hansen, Wen-Jun Liu
      Pages 143-154

    2. Serpins from an Insect, Manduca sexta

      • Michael R. Kanost, Haobo Jiang
      Pages 155-161

    3. The Significance of Serpins in the Regulation of Proteases in the Male Genital Tract

      • Anders Christensson, Anders Bjartell, Hans Lilja
      Pages 163-176

  7. Inflammation

    1. Serpins and Programmed Cell Death

      • Guy S. Salvesen
      Pages 177-183

    2. C1 Inhibitor

      • Alvin E. Davis III
      Pages 185-194

    3. Serp-1, A Poxvirus-Encoded Serpin, Is Expressed as a Secreted Glycoprotein that Inhibits the Inflammatory Response to Myxoma Virus Infection

      • Piers Nash, Alexandra Lucas, Grant McFadden
      Pages 195-205
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Keywords

Reviews

`The editors have succeeded in producing a volume of work which provides many answers to questions, asked and unasked, about a critically important field of biologic research. It should be in the library of any scientist with an interest in human physiology; it would be useful to many other researchers as well.'
Chemtracts - Biochemistry and Molecular Biology, 12:10 (1999)

Editors and Affiliations

  • University of North Carolina School of Medicine, Chapel Hill, USA

    Frank C. Church

  • University of California, Irvine, USA

    Dennis D. Cunningham

  • Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, USA

    David Ginsburg

  • Duke University and Durham VA Medical Centers, Durham, USA

    Maureane Hoffman

  • Late of Monash University, Clayton, Australia

    Stuart R. Stone

  • Washington University School of Medicine, St. Louis, USA

    Douglas M. Tollefsen

Bibliographic Information

  • Book Title: Chemistry and Biology of Serpins

  • Editors: Frank C. Church, Dennis D. Cunningham, David Ginsburg, Maureane Hoffman, Stuart R. Stone, Douglas M. Tollefsen

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-5391-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1997

  • Hardcover ISBN: 978-0-306-45698-5Published: 31 December 1997

  • Softcover ISBN: 978-1-4613-7461-9Published: 29 October 2012

  • eBook ISBN: 978-1-4615-5391-5Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIX, 358

  • Topics: Biochemistry, general, Animal Physiology, Human Genetics

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