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Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Part A

  • Book
  • © 1997

Overview

Editors:
  1. Kenneth V. Honn

    1. Wayne State University, Detroit, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Santosh Nigam

    1. Free University Berlin, Berlin, Germany

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    You can also search for this editor in PubMed   Google Scholar

  3. Lawrence J. Marnett

    1. Vanderbilt University, Nashville, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 400)

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Table of contents (74 chapters)

  1. Front Matter

    Pages i-xxv
    Download chapter PDF

  2. Phospholipases

    1. Front Matter

      Pages 1-1
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    2. Regulation of Phosphoinositide Phospholipases by G-Proteins

      • J. H. Exton
      Pages 3-8

    3. The Effects of Group II Phospholipase A2 on Ras-Induced Metastasis

      • Thomas W. Davis, E. R. Boghaert, Carla J. Guthridge, Marion R. Steiner, Stephen G. Zimmer
      Pages 9-17

    4. Activation of Ca2+-Sensitive Cytosolic Phospholipase A2 (cPLA2) in Human Platelets

      • Ruth M. Kramer, Edda F. Roberts, Joseph A. Jakubowski
      Pages 19-24

    5. Involvement of Reactive Oxygen Species in Phospholipase A2 Activation: Inhibition of Protein Tyrosine Phosphatases and Activation of Protein Kinases

      • Rachel Goldman, Ernst Ferber, Uriel Zor
      Pages 25-30

    6. High Molecular Weight Phospholipase A2: Its Occurrence and Quantification in Human Colon Cancer and Normal Mucosa

      • A. S. Soydan, I. A. Tavares, P. K. Weech, N. M. Tremblay, A. Bennett
      Pages 31-37

  3. Biosynthetic Enzymes

    1. Front Matter

      Pages 39-39
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    2. (S)-Type Lipoxygenase and Cyclooxygenase Reaction Box Models Characterizing the Stereochemistry of the Dioxygenation Reaction

      • Wolf D. Lehmann
      Pages 41-45

    3. Activation of 5-Lipoxygenase in Whole Polymorphonuclear Leukocytes by Arachidonic Acid: Evidence of Cytosolic Active Enzyme

      • Luis Vila, Josep Sola
      Pages 47-56

    4. Intracellular Distribution, Activity, and Ca2+-Dependent Translocation of 12-Lipoxygenase in Lewis Lung Tumor Cells

      • Wolfgang Hagmann, Robert Maher, Kenneth V. Honn
      Pages 57-64

    5. Cloning and Sequencing of Prostaglandin H Synthetase from Rat Tracheal Epithelial Cells: Structural Evidence that a TPA Regulated mRNA Codes for the Rat Ortholog of Murine PHS-1

      • J. Kitzler, R. Hardman, E. Hill, N. Reddy, R. Philpot, T. E. Eling
      Pages 65-70

    6. Non-Enzymatic Rearrangement of Leukotriene A4 to 5-Keto-(7E,9E,11Z,14Z)-Eicosatetraenoic Acid in Aqueous Media

      • D. Riendeau, J.-P. Falgueyret, J. Gravel, L. Trimble, J. Yergey
      Pages 71-76

    7. Bromoacetamido-Analogs of Indomethacin and Mefenamic Acid Affinity-Label Prostaglandin H2 Synthase at Two Sites

      • Mark S. Tang, Leslie J. Askonas, Trevor M. Penning
      Pages 77-84

    8. Regulation of Eicosanoid Synthesis in Liver Macrophages

      • Petra Ambs, Edith Fitzke, Peter Dieter
      Pages 85-92

    9. Comparison of Arachidonic Acid Metabolism by Normal, Pre-Cancerous and Neoplastic Epithelial Cell Lines of the Upper Aerodigestive Tract

      • Carl Snyderman, Donald Schwartz, Carrie Bonomi, Robin Wagner
      Pages 93-98

    10. Induction of Prostaglandin Endoperoxide Synthase-1 (Cox-1) in a Human Promonocytic Cell Line by Treatment with the Differentiating Agent TPA

      • Christopher J. Smith, Jason D. Morrow, L. Jackson Roberts II, Lawrence J. Marnett
      Pages 99-106

    11. X-Ray Crystallographic Study of the Structure of Prostaglandin H Synthase

      • Daniel Picot, Patrick J. Loll, R. Michael Garavito
      Pages 107-111

    12. Properties of Prostacyclin Synthase

      • V. Ullrich, R. Brugger, F. Lottspeich, I. Siegle
      Pages 113-119

    13. Regulation of Prostaglandin H Synthase-1 Gene Expression

      • Kenneth K. Wu
      Pages 121-126
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Keywords

About this book

Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Editors and Affiliations

  • Wayne State University, Detroit, USA

    Kenneth V. Honn

  • Free University Berlin, Berlin, Germany

    Santosh Nigam

  • Vanderbilt University, Nashville, USA

    Lawrence J. Marnett

Bibliographic Information

  • Book Title: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

  • Book Subtitle: Part A

  • Editors: Kenneth V. Honn, Santosh Nigam, Lawrence J. Marnett

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-5325-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1997

  • Hardcover ISBN: 978-0-306-45360-1Published: 28 February 1998

  • Softcover ISBN: 978-1-4613-7430-5Published: 17 October 2012

  • eBook ISBN: 978-1-4615-5325-0Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXV, 555

  • Topics: Biochemistry, general, Immunology

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