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Principles of Cardiovascular Neural Regulation in Health and Disease

  • Book
  • © 2000

Overview

Authors:
  1. Alberto Malliani

    1. Centro Ricerche Cardiovascolari, CNR, Università di Milano, Italy
      Dipartimento Scienze Precliniche LITA-Vialba, Università di Milano, Italy
      Dipartimento di Medicina Interna, Ospedale “L. Sacco”, Università di Milano, Italy

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Part of the book series: Basic Science for the Cardiologist (BASC, volume 6)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xvii
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  2. General Concepts and Hypotheses in the Study of Cardiovascular Neural Regulation

    • Alberto Malliani
    Pages 1-30

  3. Pathophysiological Mechanisms and the Loss of a Finalistic Purpose

    • Alberto Malliani
    Pages 31-64

  4. The Sympathovagal Balance Explored in the Frequency Domain

    • Alberto Malliani
    Pages 65-107

  5. Pathophysiological Alterations of Sympathovagal Balance

    • Alberto Malliani
    Pages 109-147

  6. Variability and Nonlinear Dynamics

    • Alberto Malliani
    Pages 149-168

  7. The Necessary Apical Principle in Science and Medicine

    • Alberto Malliani
    Pages 169-180

  8. Back Matter

    Pages 181-222
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Keywords

About this book

This book is an attempt to indicate to researchers and clinicians a simple way to approach the complexity of cardiovascular neural regulation. A conceptual pillar like homeostasis is contrasted with instability and a continuous interaction of opposing mechanisms that have negative and positive feedback characteristics, and is considered to subserve the multitude of patterns pertaining to physiology. However, in pathophysiological conditions the final design is most often replaced by largely purposeless neural mechanisms.
The complexity of cardiovascular neural regulation, reflected by the state of sympathovagal balance, is also assessed in the frequency domain. Power spectrum analysis of heart rate and arterial pressure variability, a sophisticated but simply explained approach, provides an unprecedented tool to evaluate this interaction in both physiological and pathophysiological conditions. The elementary characteristics of nonlinear dynamics are also outlined. Finally, the need for an ethical structure for science and medicine is analyzed.

Authors and Affiliations

  • Centro Ricerche Cardiovascolari, CNR, Università di Milano, Italy

    Alberto Malliani

  • Dipartimento Scienze Precliniche LITA-Vialba, Università di Milano, Italy

    Alberto Malliani

  • Dipartimento di Medicina Interna, Ospedale “L. Sacco”, Università di Milano, Italy

    Alberto Malliani

Bibliographic Information

  • Book Title: Principles of Cardiovascular Neural Regulation in Health and Disease

  • Authors: Alberto Malliani

  • Series Title: Basic Science for the Cardiologist

  • DOI: https://doi.org/10.1007/978-1-4615-4383-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2000

  • Hardcover ISBN: 978-0-7923-7775-7Published: 31 March 2000

  • Softcover ISBN: 978-1-4613-6971-4Published: 26 October 2012

  • eBook ISBN: 978-1-4615-4383-1Published: 06 December 2012

  • Series ISSN: 1566-0753

  • Edition Number: 1

  • Number of Pages: XVII, 222

  • Topics: Cardiology, Neurology

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