Skip to main content
SpringerLink
Log in
Book cover
  • Book
  • © 1990

Selective Activation of Drugs by Redox Processes

Editors:

  1. G. E. Adams

    1. MRC Radiobiology Unit, Chilton, Oxon., UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. A. Breccia

    1. Facoltà di Farmacia, Istituto di Scienze Chimiche, Università Degli Studi di Bologna, Bologna, Italy

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. E. M. Fielden

    1. MRC Radiobiology Unit, Chilton, Oxon., UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. P. Wardman

    1. CRC Gray Laboratory, Mount Vernon Hospital, Middlesex, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 198)

Sections

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (31 chapters)

  1. Front Matter

    Pages i-xi
    PDF

  2. Characteristics of Hypoxic Cells that Enhance their Susceptibility to Chemical Injury

    • Dean P. Jones, Tak Yee Aw, Xiaoqin Shan, Diane L. Tribble
    Pages 1-9

  4. Metal-Catalyzed Redox Processes in Biological Systems and Drug Activation

    • A. Breccia, E. Gattavecchia, E. Vecchi, E. Ferri
    Pages 25-37

  6. The Role of DNA Damage in the Bioreductive Action of 2-Nitroimidazoles

    • P. O’Neill, T. J. Jenner, O. Sapora, P. W. Crump, S. M. T. Cunniffe, E. M. Fielden
    Pages 53-61

  9. Redox Activation of Drugs by the Red Blood Cell Membrane

    • J. Z. Pedersen, L. Rossi, L. Marcocci, I. Mavelli, G. Rotilio
    Pages 89-95

  14. Nitroacridines and Nitroquinolines as DNA-Affinic Hypoxia-Selective Cytotoxins

    • William A. Denny, William R. Wilson, Graham J. Atwell, Maruta Boyd, Susan M. Pullen, Robert F. Anderson
    Pages 149-158

  15. Metabolic Effects of Hypoxic Cell Sensitizers

    • Christian Streffer, Peter Tamulevicius
    Pages 159-164

  16. Does Ro 03–8799 Concentration in Human Tumour Xenografts Predict Radiosensitization? Comparison with SR-2508

    • Marcelle Guichard, Alphonse Taghian, Francoise Lespinasse, Edmond Philippe Malaise
    Pages 165-172

  17. Enzyme-Directed Bioreductive Drug Development

    • Paul Workman, Michael I. Walton
    Pages 173-191

  18. Improved Treatment of Tumours in vivo by Combining the Bioreductive Drug RSU-1069, Hydralazine and Hyperthermia

    • Michael R. Horsman, Kent L. Christensen, David J. Chaplin, Jens Overgaard
    Pages 193-202

  19. The Assessment of Bioreductive Drug Toxicity in vitro and in Experimental Tumours in vivo

    • I. J. Stratford, G. E. Adams, J. C. M. Bremner, S. Cole, Li Ding, H. Edwards et al.
    Pages 203-212
Back to top

Keywords

Back to top

Editors and Affiliations

  • MRC Radiobiology Unit, Chilton, Oxon., UK

    G. E. Adams, E. M. Fielden

  • Facoltà di Farmacia, Istituto di Scienze Chimiche, Università Degli Studi di Bologna, Bologna, Italy

    A. Breccia

  • CRC Gray Laboratory, Mount Vernon Hospital, Middlesex, UK

    P. Wardman

Back to top

Bibliographic Information

  • Book Title: Selective Activation of Drugs by Redox Processes

  • Editors: G. E. Adams, A. Breccia, E. M. Fielden, P. Wardman

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4615-3768-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1990

  • Hardcover ISBN: 978-0-306-43735-9Published: 28 February 1991

  • Softcover ISBN: 978-1-4613-6679-9Published: 21 October 2012

  • eBook ISBN: 978-1-4615-3768-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 361

  • Topics: Oncology, Pharmacology/Toxicology, Biochemistry, general

Back to top

Publish with us

Policies and ethics

Back to top
Access via your institution

Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Search

Navigation