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Vascular Endothelium

Physiological Basis of Clinical Problems

  • Book
  • © 1991

Overview

Editors:
  1. John D. Catravas

    1. Medical College of Georgia, Augusta, USA

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  2. Allan D. Callow

    1. Washington University Medical Center, St. Louis, USA

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  3. C. Norman Gillis

    1. Yale University, New Haven, USA

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  4. Una S. Ryan

    1. Monsanto Company, St. Louis, USA

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Part of the book series: NATO Science Series A: (NSSA, volume 208)

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Table of contents (67 chapters)

  1. Front Matter

    Pages i-x
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  3. General Concepts in Endothelial Cell Pathophysiology

    1. Front Matter

      Pages 53-53
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    2. Free-Radical Mediated Actions on Endothelial Cells of the Intact Lung

      • C. Norman Gillis, X. Chen, M. Merker
      Pages 55-67

    3. Regulation of Vascular Function by Vascular Permeability Factor

      • Daniel T. Connolly
      Pages 69-76

  4. Chemical Mediators of Endothelial Cell Injury

    1. Front Matter

      Pages 77-77
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    2. Endothelial Cells as Targets for and Producers of Cytokines

      • E. Dejana, G. Bazzoni, I. Martin-Padura, S. Walter, Alberto Mantovani
      Pages 79-85

    3. Roles of Vascular Cells in Inflammation and Immunopathology

      • Peter Libby
      Pages 87-95

    4. The Biochemistry, Cell and Molecular Biology of Type 1 Plasminogen Activator Inhibitor

      • David J. Loskutoff
      Pages 97-107

  5. Endothelial Cell Interaction with Blood Components

    1. Front Matter

      Pages 109-109
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    2. Purine Regulation of Endothelial Cells: Relevance to Pathophysiology

      • John L. Gordon
      Pages 111-116

    3. Autoantibodies to Endothelial Cells

      • Jeremy D. Pearson
      Pages 117-125

    4. Leukocyte-Endothelial Cell Interactions

      • James Varani
      Pages 127-135

  6. Vascular Responses to Endothelial Cell Injury

    1. Front Matter

      Pages 137-137
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    2. Endothelium Function in Human Coronary Bypass Grafts

      • Thomas F. Lüscher, Z. Yang
      Pages 139-155

    3. Altered Renovascular Endothelial Functions During Nephrotoxicity

      • N. Perico, C. Zoja, Giuseppe Remuzzi
      Pages 157-166
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Keywords

About this book

This monograph contains the proceedings from the Advanced Study Institute on "Vascular Endothelium: Physiological Basis of Clinical Problems" which took place in Corfu, Greece in June 1990. The meeting consisted of twenty-eight lectures, most of them adapted as full length papers in this volume, as well as numerous short oral and poster communications which are abstracted and also included in alphabetical order (pages 239-302). There were ninety-six participants from ten NATO and four other European countries. The meeting was the second in as many years dealing with a specific subject in Endothelial Cell biology. Following the 1988 discussion on "Receptors and Transduction Mechanisms", the present ASI recognized and tried to deal with the increasing overlap in interest between basic scientists studying endothelial cell functions and clinicians facing problems of known or suspected endothelial pathological involvement. As with any similar effort, we opted to be selective, rather than fail by trying to be inclusive, in the subjects covered. We chose to discuss diseases, such as atherosclerosis, sepsis, ARDS and stroke, based on their relevance to endothelial cell function and urgent need for new insights into their pathogenesis and treatment. Similarly, we examined endothelial cell functions by considering their relevance to disease and their potential for elucidating important pathologies. Obviously, some areas were covered superficially or not at all; this should not distract from their importance, but rather reflect on the constraints of time and -not at all negligibly -the bias of the organizing committee.

Editors and Affiliations

  • Medical College of Georgia, Augusta, USA

    John D. Catravas

  • Washington University Medical Center, St. Louis, USA

    Allan D. Callow

  • Yale University, New Haven, USA

    C. Norman Gillis

  • Monsanto Company, St. Louis, USA

    Una S. Ryan

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