Photobiology

1. Front Matter

   Pages i-xviii

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2. Opening of the Congress

   1. Opening of the Congress

      • R. Latarjet

      Pages 1-2

3. AIP President Lecture

   1. Themes and Trends in Photobiology

      • K. K. Rohatgi-Mukherjee

      Pages 3-11

4. A Half Century of Photobiology: The Alexander Hollaender Memorial Symposium

   1. Front Matter

      Pages 13-13

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   2. Alexander Hollaender (1898-1986)

      • R. Latarjet

      Pages 15-16

   3. Alexander Hollaender: The Man and His Work*

      • R. B. Setlow

      Pages 17-20

   4. Defective DNA Repair and Human Disease

      • A. R. Lehmann

      Pages 21-26

   5. DNA-Protein Crosslinking in UV-Irradiated Human and ICR 2A Cell Lines

      • Barry S. Rosenstein, Li-Wen Lai

      Pages 27-34

   6. Retroviral Based Shuttle Vectors and Endogenous Cellular Genes: Complementary Approaches for Investigations of Mutational Specificity

      • E. A. Drobetsky, A. J. Grosovsky, A. Skandalis, L. R. Shekter, B. W. Glickman

      Pages 35-40

5. Ultraviolet and Ionizing Radiations: From Molecules to Cells

   1. Front Matter

      Pages 41-41

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   2. Photobiology and Radiobiology: Divisions and Common Ground

      • J. Z. Beer

      Pages 43-48

   3. Comparative Effects of Ultraviolet and Ionizing Radiations on Nucleic Acids

      • Jean Cadet, Maurice Berger, Prakash C. Joshi, Anthony Shaw, Lucienne Voituriez, Lou-Sing Kan et al.

      Pages 49-59

   4. Interaction Between Ultraviolet and Ionizing Radiation in Eukaryotic Cells

      • J. Kiefer

      Pages 61-69

   5. A Molecular Model for the Cytotoxic Action of UV and Ionizing Radiation

      • H. P. Leenhouts, K. H. Chadwick

      Pages 71-81

   6. Mutagenic Effects of Ultraviolet and Ionizing Radiation

      • Helen H. Evans

      Pages 83-95

   7. Malignant Transformation by Ultraviolet and Ionizing Radiations

      • J. B. Little

      Pages 97-103

   8. Between Ultraviolet and Ionizing Radiation: Action Spectra for Cytotoxicity in the Vacuum-UV Region

      • Takashi Ito

      Pages 105-111

6. UV Light and DNA Damage Repairs and Mutagenesis

   1. Front Matter

      Pages 113-113

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   2. Brief Methodological Survey of the Photochemistry of Nucleic Acid Constituents and Analogues, and Some Biological Applications, Including Photo-Affinity Labeling

      • David Shugar, Borys Kierdaszuk, Ryszard Stolarski

      Pages 115-133

   3. The Sequence Specificity of Ultraviolet Light Damage to DNA Containing Bromodeoxyuridine or Iododeoxyuridine

      • V. Murray, R. F. Martin

      Pages 135-140

It is not always the case that the subject of a scientific book and its relevance to everyday li fe are so timely. Photobiology and its si ster subject Radiobiology are now a must for understanding the environment we live in and the impact light, ultraviolet light, and radiation have on all aspects of our life. Photobiology is a true interdisciplinary field. Photobiology research plays a direct role in diverse fields, and a glance at the topics of the symposia covered in this book by over 100 articles shows the breadth and depth of knowledge acquired in fundamental research and its impact on the major issues and applied problems the world is facing. Half a century of photobiology research brought about an understanding of the importance of light to life, both as a necessary source of energy and growth as weIl as its possible dangers. Research in photochemistry and photobiology led to the discoveries of ceIlular repair mechanisms of UV induced damages to DNA and this led to understanding of the effects of hazardous environmental chemieals and mutagenecity , and to the development of genetic engineering. This topic was given due emphasis in several symposia and chapters in this book.

• Chloroplast
• DNA
• Nucleotide
• bacteria
• brain
• development
• diagnosis
• enzymes
• growth
• mutation
• nucleic acid
• photosynthesis
• radiation
• radiobiology
• receptor
• Ultrasonography

• Israel Atomic Energy Commission, Beer-Sheva, Israel

  Emanuel Riklis

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