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Developmental Neuropathology of Schizophrenia

  • Book
  • © 1991

Overview

Editors:
  1. Sarnoff A. Mednick

    1. University of Southern California, Los Angeles, USA

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  2. Tyrone D. Cannon

    1. University of Southern California, Los Angeles, USA

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  3. Christopher E. Barr

    1. University of Southern California, Los Angeles, USA

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  4. José M. LaFosse

    1. University of Southern California, Los Angeles, USA

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Part of the book series: NATO Science Series A: (NSSA, volume 217)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-viii
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  2. The Developing Brain

    1. The Internal Environment of the Developing Brain

      • Katarzyna M. Dziegielewska, Norman R. Saunders
      Pages 1-28

    2. Neuronal Migration and Differentiation during Normal and Genetically Perturbed Development of the Hippocampal Formation

      • Richard S. Nowakowski
      Pages 29-60

  4. Neuropathological Indicants of Neurodevelopmental Anomalies in Schizophrenics

    1. Clinical and Neurodevelopmental Aspects of Brain Pathology in Schizophrenia

      • Bernhard Bogerts, Peter Falkai
      Pages 93-120

  5. Perinatal Complications in Schizophrenics

    1. Obstetrical Events and Adult Schizophrenia

      • Karen L. Dykes, Sarnoff A. Mednick, Tyrone D. Cannon, Christopher E. Barr
      Pages 121-140

  6. Structural Imaging and Neuropsychological Evidence of Neurodevelopmental Anomalies

    1. Structural Brain Measurements on MRI Scans in Schizophrenia: Evidence of Neurodevelopmental Pathology

      • Henry A. Nasrallah, Steven B. Schwarzkopf, Stephen C. Olson
      Pages 141-147

    2. The Possible Neurodevelopmental Significance of Structural Imaging Findings in Schizophrenia

      • Tyrone D. Cannon
      Pages 149-166

    3. Morphologic Markers of Neurodevelopmental Paths to Schizophrenia

      • Robert M. Bilder, Gustav Degreef
      Pages 167-190

  7. Facts About Schizophrenia and Neurodevelopment

    1. Neurodevelopment and the Chronological Curiosities of Schizophrenia

      • P. B. Jones, R. Goodman, M. J. Owen, S. W. Lewis, R. M. Murray
      Pages 191-209

    2. A Neurodevelopmental Approach to Schizophrenia Research

      • Jose M. LaFosse, Sarnoff A. Mednick
      Pages 211-225

  8. Back Matter

    Pages 227-247
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Keywords

About this book

This volume reports the proceedings of a NATO Advanced Workshop held in Castelvecchio Pas coli, Italy, from August 28 - September 1, 1989. An important inspiration for this Workshop came from our studies in Helsinki and Denmark, which have found that exposure to an influenza epidemic during the second trimester of fetal development increases the risk of adult schizophrenia. This finding has stimulated an important new hypothesis in the study of the etiology of schizophrenia. It has suggested the possiblity that disturbances of brain development during gestation may contribute to the risk of adult schizophrenia. We determined that it would be of value to bring together schizophrenia researchers and those doing basic studies of the development of the brain. Both groups of researchers were encouraged to communicate at a level that would help other scientists to integrate their knowledge and techniques into their own discipline. For this reason, perhaps, the papers of this volume are remarkably clear and not difficult to understand. The first four chapters describe the neurochemical and structural aspects of brain development. The chapter by Dziegielewska and Saunders discusses transport mechanisms and the properties of endogenous and exogenous substances that control the internal environment of the developing brain. In the second chapter, Nowakowski reports on his studies of the develop­ ment of the hippocampus in mice genetically inbred to exhibit disruptions of neural migration.

Editors and Affiliations

  • University of Southern California, Los Angeles, USA

    Sarnoff A. Mednick, Tyrone D. Cannon, Christopher E. Barr, José M. LaFosse

Bibliographic Information

  • Book Title: Developmental Neuropathology of Schizophrenia

  • Editors: Sarnoff A. Mednick, Tyrone D. Cannon, Christopher E. Barr, José M. LaFosse

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4615-3378-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1991

  • Hardcover ISBN: 978-0-306-44081-6Published: 30 April 1992

  • Softcover ISBN: 978-1-4613-6491-7Published: 23 October 2012

  • eBook ISBN: 978-1-4615-3378-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 247

  • Topics: Psychiatry, Developmental Biology, Human Genetics, Neurosciences, Neuropsychology

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