Modern Trends in Biothermokinetics

1. Front Matter

   Pages i-xiv

   PDF

2. Thermodynamics and Kinetics of Transport Processes and Biological Energy Transduction

   1. Front Matter

      Pages 1-1

      PDF

   2. Frontiers in the Mathematical Description of “Biothermokinetic” Phenomena

      • G. Rickey Welch

      Pages 3-6

   3. Monitoring a Heterogeneous Coupled System Using Soluble and Biologically Localized Firefly Luciferase as a Probe for Bulk and Local [ATP]

      • Claude Aflalo

      Pages 7-10

   4. Control of Cytochrome C Oxidase: Kinetic, Thermodynamic or Allosteric?

      • Peter Nicholls

      Pages 11-16

   5. Mechanism of Bupivacaine Uncoupling in Rat Heart Mitochondria

      • F. Sztark, P. Schönfeld, P. Dabadie, J.-P. Mazat

      Pages 17-22

   6. Mosaic Non-Equilibrium Thermodynamics as a Tool in the Study of Oxidative Phosphorylation

      • B. H. Groen, J. A. Berden, K. van Dam

      Pages 23-26

   7. The Redox State of Cytochromes as a New Tool to Assess the Thermodynamic State of Mitochondria

      • Siro Luvisetto, Ibolya Schmehl, Marcella Canton, Giovanni Felice Azzone

      Pages 27-32

   8. Thermodynamic Response Paradigm and Its Application to Oxidative Phosphorylation

      • Bernard Korzeniewski, Wojciech Froncisz

      Pages 33-38

   9. A Model Study on the Interrelation between the Transmembrane Potential and pH Difference Across the Mitochondrial Inner Membrane

      • Stefan Schuster, Jean-Pierre Mazat

      Pages 39-44

   10. Comparison of Retinal-Based and Chlorophyll-Based Photosynthesis: A Biothermokinetic Description of Photochemical Reaction Centers

       • Klaas J. Hellingwerf, Wim Crielaard, Hans V. Westerhoff

       Pages 45-52

   11. Regulation of Energy Flux of Yeast during Steady State and Oscillatory Growth

       • Regine Ölz, Katrin Larsson, Christer Larsson, Erich Gnaiger, Lena Gustafsson

       Pages 53-60

   12. Free-Energy Coupling Mediated by Dynamic Interactions between Membrane Proteins

       • R. Dean Astumian, Baldwin Robertson, Martin Bier

       Pages 61-66

   13. Characterization of Energy-Dependent Phosphate Uptake by Blue-Green Alga Anacystis Nidulans: Adaptation to External Phosphate Levels Obeys a Linear Flow-Force Relation

       • Gernot Falkner, Ferdinand Wagner, Renate Falkner

       Pages 67-70

   14. Brownian Dynamics Simulation of Charged Membrane Components: Implications for their Lateral Distribution and Voltage Dependence of Ion Transport through Membranes

       • Dirk Walther, Peter Kuzmin, Edwin Donath

       Pages 71-76

   15. Evolutionary Strategies and the Optimization of Carrier Models

       • J. Lenz, M. Höfer

       Pages 77-81

3. Modeling of Cell Processes with Applications to Biotechnology and Medicine

   1. Front Matter

      Pages 83-83

      PDF

   2. Mathematical Model of the Creatine Kinase Reaction Coupled to Adenine Nucleotide Translocation and Oxidative Phosphorylation

      • Mayis K. Aliev, Valdur A. Saks

      Pages 85-92

   3. Critical Regulation of Multienzyme Complexes: A Kinetic Model for the Mammalian Pyruvate Dehydrogenase Complex

      • Boris N. Goldstein, Vitalii A. Selivanov

      Pages 93-96

   4. The Analysis of Flux in Substrate Cycles

      • David A. Fell

      Pages 97-101

This book includes articles relating to presentations given in a variety of forms (lectures, posters, contributions to round tables, software presentations) at the 5th International Biothermokinetics Meeting held in Bordeaux-Bombannes, September 23-26, 1992. The fact that not just lectures were considered for these proceedings reflects the aims of BTK meetings to instigate discussion, promote scientific cooperation and confront as many different ideas as possible with each other (at best heretical ones). BTK conferences have expanded more and more; 130 participants came to the 1992 meeting from 20 countries. It was therefore necessary to hold the round tables in parallel sessions. It is difficult to have an unbiased feeling of what should be selected as the salient features of the meeting. As the name suggests, Biothermokinetics embraces thermodynamic and kinetic approaches to experimental and theoretical investigations of biological processes, in particular at the cellular level. This "classical" point of view is mainly represented in the chapter "Thermodynamics and Kinetics of Transport Processes and Biological Energy Transduction".

• development
• enzyme
• enzymes
• mitochondria
• phosphorylation
• respiration
• thermodynamics

• University of Bordeaux II, Bordeaux, France

  Stefan Schuster, Rachid Ouhabi, Jean-Pierre Mazat

• Institute of Cellular Biochemistry, CNRS, Bordeaux, France

  Michel Rigoulet

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