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The Chemokines

Biology of the Inflammatory Peptide Supergene Family II

  • Book
  • © 1993

Overview

Editors:
  1. I. J. D. Lindley

    1. Sandoz Research Institute, Vienna, Austria

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  2. J. Westwick

    1. University of Bath, Bath, UK

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  3. S. Kunkel

    1. University of Michigan, Ann Arbor, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 351)

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Table of contents (77 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Symposium Presentations

    1. Chemotactic and Inflammatory Cytokines — CXC and CC Proteins

      • Marco Baggiolini
      Pages 1-11

    2. Induction of Chemotactic Cytokines by Minimally Oxidized Ldl

      • Judith A. Berliner, David S. Schwartz, Mary C. Territo, Ali Andalibi, Laura Almada, Aldons J. Lusis et al.
      Pages 13-18

    3. The Immunopathology of Chemotactic Cytokines

      • Robert M. Strieter, Steven L. Kunkel
      Pages 19-28

    4. Receptor/Ligand Interactions in the C-C Chemokine Family

      • Thomas J. Schall, John Y. Mak, David DiGregorio, Kuldeep Neote
      Pages 29-37

    5. Adhesion Molecules in Acute and Chronic Lung Inflammation

      • L. Gordon Letts, Craig D. Wegner, Robert H. Gundel
      Pages 39-45

    6. Monocyte Chemotactic Protein-1 (MCP-1): Signal Transduction and Involvement in the Regulation of Macrophage Traffic in Normal and Neoplastic Tissues

      • Alberto Mantovani, Silvano Sozzani, Barbara Bottazzi, Giuseppe Peri, Francesca Luisa Sciacca, Massimo Locati et al.
      Pages 47-54

    7. Secretion of Monocyte Chemoattractant Protein-1 (MCP-1) by Human Mononuclear Phagocytes

      • Edward J. Leonard, Alison Skeel, Teizo Yoshimura, John Rankin
      Pages 55-64

    8. L-Arginine/Nitric Oxide Pathway: A Possible Signal Transduction Mechanism for the Regulation of the Chemokine IL-8 in Human Mesangial Cells

      • Zarin Brown, Rachel L. Robson, John Westwick
      Pages 65-75

    9. Some Aspects of NAP-1/IL-8 Pathophysiology II: Chemokine Secretion by Exocrine Glands

      • Antal Rot, Anne P. Jones, Louise M. C. Webb
      Pages 77-85

    10. Molecular Mechanism of Interleukin-8 Gene Expression

      • Shu-ichi Okamoto, Naofumi Mukaida, Kazuo Yasumoto, Hyogo Horiguchi, Kouji Matsushima
      Pages 87-97

    11. Basophil Activation by Members of the Chemokine Superfamily

      • Clemens A. Dahinden, Martin Krieger, Thomas Brunner, Stephan C. Bischoff
      Pages 99-110

    12. Monocyte Chemotactic Proteins Related to Human MCP-1

      • Jo Van Damme, Paul Proost, Jean-Pierre Lenaerts, René Conings, Ghislain Opdenakker, Alfons Billiau
      Pages 111-118

    13. Platelets Secrete an Eosinophil-Chemotactic Cytokine which is a Member of the C-C-Chemokine Family

      • Jens-Michael Schröder, Yoshikazu Kameyoshi, Enno Christophers
      Pages 119-127

    14. Neutrophil-Activating Peptide ENA-78

      • Alfred Walz, Robert M. Strieter, Silvia Schnyder
      Pages 129-137

    15. The Effects of Human Recombinant MIP-1α, MIP-1β, and Rantes on the Chemotaxis and Adhesion of T Cell Subsets

      • Dennis D. Taub, Andrew R. Lloyd, Ji-Ming Wang, Joost J. Oppenheim, David J. Kelvin
      Pages 139-146

    16. Promiscuity of Ligand Binding in the Human Chemokine Beta Receptor Family

      • David J. Kelvin, Ji-Ming Wang, Dan McVicar, Joost J. Oppenheim
      Pages 147-153

    17. Structural and Functional Characterization of the Interleukin-8 Receptors

      • M. Patricia Beckmann, Richard B. Gayle, Douglas Pat Cerretti, Carl J. March, Subhashini Srinivasan, Paul R. Sleath
      Pages 155-169

    18. Elucidation of Structure Function Relationships in the IL-8 Family by X-ray Crystallography

      • Manfred Auer, Susan R. Owens, Sabine Pfeffer, Joerg Kallen, Erich Wasserbauer, Heinz Aschauer et al.
      Pages 171-182

    19. Overview of Chemokines

      • Joost J. Oppenheim
      Pages 183-186
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Keywords

About this book

The first symposium in this series was held at the Royal College of Surgeons of England in December 1988 and was entitled "Novel Neutrophil Stimulating Peptides". That symposium successfully brought together the majority of laboratories working in the area of interleukin-8 and related peptides; see Immunology Today 10: 146-147 (1989). The Second International Symposium on Chemotactic Cytokines was held at the same venue in June 1990, and a much-increased attendance reflected the accelerating pace of work in the area of these chemotactic cytokines. The proceedings of that meeting were published in Advances in Experimental Medicine and Biology, vol. 305 (1991). The rapid advances made in the field of chemotactic cytokines over the last 18 months necessitated a third Symposium in this series to collate and place in perspective an explosion of new data. The Third International Symposium on Chemotactic Cytokines was held between August 31 and September 1, 1992 in Baden-bei-Wien, Austria. However, the lack of a clear nomenclature system was creating some confusion in the area, especially as new factors continue to be discovered and classified as family members. In the past, these inflammatory mediators had been placed arbitrarily under the broad heading of "intercrines" or "chemotactic cytokines" with no clear classification guidelines to follow. This nomenclature issue was addressed at the Symposium, where investigators in the field were invited to reach a consensus regarding a collective name for these mediators. The resulting decision was to identify the major family as chemokines, to replace all previous terms.

Editors and Affiliations

  • Sandoz Research Institute, Vienna, Austria

    I. J. D. Lindley

  • University of Bath, Bath, UK

    J. Westwick

  • University of Michigan, Ann Arbor, USA

    S. Kunkel

Bibliographic Information

  • Book Title: The Chemokines

  • Book Subtitle: Biology of the Inflammatory Peptide Supergene Family II

  • Editors: I. J. D. Lindley, J. Westwick, S. Kunkel

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-2952-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1993

  • Hardcover ISBN: 978-0-306-44710-5Published: 30 June 1994

  • Softcover ISBN: 978-1-4613-6283-8Published: 18 October 2012

  • eBook ISBN: 978-1-4615-2952-1Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XV, 227

  • Topics: Immunology, Pharmacology/Toxicology, Biochemistry, general

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