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Neural Development and Schizophrenia

Theory and Research

  • Book
  • © 1995

Overview

Editors:
  1. Sarnoff A. Mednick

    1. University of Southern California, Los Angeles, USA

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  2. J. Meggin Hollister

    1. University of Southern California, Los Angeles, USA

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Part of the book series: NATO Science Series A: (NSSA, volume 275)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-x
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  2. Introduction

    1. A Multidisciplinary Approach to the Neurodevelopment of Schizophrenia

      • J. Meggin Hollister, Ricardo A. Machon, Sarnoff A. Mednick
      Pages 1-11

  4. Pathology of the Brain of Schizophrenics: Implications for Neurodevelopment

  5. Premorbid Signs and Clinical Characteristics of Schizophrenia

    1. Childhood Risk Factors for Adult Schizophrenia in a General Population Birth Cohort at Age 43 Years

      • Peter Jones, Robin Murray, Bryan Rodgers
      Pages 151-176

    2. Subtypes of Schizophrenia: Diagnostic and Conceptual Issues

      • Pekka Tienari, Lyman C. Wynne
      Pages 177-189

  6. Fetal Neurodevelopmental Disturbance: Sources and Consequences

    1. Fetal Viral Infections

      1. Fetal Viral Infection and Adult Schizophrenia: Empirical Findings and Interpretation
        • Ricardo A. Machón, Sarnoff A. Mednick, Matti O. Huttunen
        Pages 191-202
      2. How Can We Judge Whether Or Not Prenatal Exposure to Influenza Causes Schizophrenia?
        • John McGrath, David Castle, Robin Murray
        Pages 203-214

    2. Aniibody Exposure

      1. Disruption of Fetal Brain Development by Maternal Antibodies as an Etiological Factor in Schizophrenia
        • Peter Laing, John G. Knight, Pádraig Wright, William L. Irving
        Pages 215-246

  7. Back Matter

    Pages 247-262
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Keywords

About this book

This is the third meeting we have organized which has explored the meaning of fetal neural developmental disruption in the etiology of schiwphrenia. The first was sponsored by the Schiwphrenia Research Branch with the scientific cooperation of Dr. David Shore. We met in Washington; the output of the meeting was published in a book entitled, Fetal Neural Development and Adult Schizophrenia. Cambridge University Press. 1991. The next meeting was an Advanced Research Workshop sponsored by NATO and was held at n Ciocco. Castelvecchio Pascoli. This meeting was reported in a NATO volume. Developmental Neuropathology of Schizophrenia and was edited by Mednick. Cannon. Barr and La Fosse. The current meeting has noted several advances in the field. There are additional psychiatric illnesses which have been found to be related to maternal viral infection in the second trimester. There have been studies reported which have definitely observed a viral infection in the mothers of fetuses who later evidenced schirophrenia. More evidence has been published which has replicated the "second-trimester effect." In the future studies will be wise to provide serological evidence of a viral infection and information on the precise viruses involved. Another important step will be to determine whether second-trimester maternal viral infection is related to a behavioral deficit in the infant. If neural development has been compromised. it might be possible to detect deficits in the infant with the proper measures. We look forward to future meetings at which these new areas might be explored.

Editors and Affiliations

  • University of Southern California, Los Angeles, USA

    Sarnoff A. Mednick, J. Meggin Hollister

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