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Cardiovascular Physiology in the Genetically Engineered Mouse

  • Book
  • © 2002

Overview

Editors:
  1. Brian D. Hoit

    1. Case Western Reserve University and University Hospitals of Cleveland, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Richard A. Walsh

    1. Case Western Reserve University and University Hospitals of Cleveland, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 238)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Part One

    1. The Hierarchical Approach to Analysis of Cardiovascular Function in Mice: An Overview

      • Richard A. Walsh
      Pages 1-16

    2. Genetic Alterations and Modeling of Cardiovascular Physiology

      • Albrecht G. Schmidt, Vivek J. Kadambi, Karen B. Young, Evangelia G. Kranias
      Pages 17-38

    3. Conditional Transgenesis

      • Tetsuo Minamino, Michael D. Schneider
      Pages 39-52

    4. Array Transcription Profiling: Molecular Phenotyping of Rodent Cardiovascular Models

      • Susan Acton, Raju Jeyaseelan, Vivek J. Kadambi, Roger E. Breitbart
      Pages 53-61

    5. Murine Cardiovascular Development

      • Steven A. Fisher
      Pages 63-69

  3. Part Two

    1. Isolated Myocyte Mechanics and Calcium Transients

      • Zhi Su, William H. Barry
      Pages 71-89

    2. Single Cell Patch-Clamp Analysis of Mouse Cardiac Myocytes

      • Nipavan Chiamvimonvat, M. Jane Lalli, Atsuko Yatani
      Pages 91-112

    3. The Isolated Isovolumic (Langendorff) Heart Preparation

      • Martin M. LeWinter
      Pages 113-127

    4. The Isolated Work-Performing and Ejecting Mouse Heart Preparation Comparison and Quantification of Cardiac Performance in Transgenic and Wild-Type Mice

      • Ingrid L. Grupp, Jo El Schultz, George Sfyris, Gunter Grupp
      Pages 129-150

    5. 31P NMR Spectroscopy of the Mouse Heart

      • Joanne S. Ingwall, Maryam M. Javadpour, Wenfeng Miao
      Pages 151-163

    6. Electrophysiological Characterization of the Mouse Heart Using Voltage-Sensitive Dyes

      • Benjamin C. Eloff, David S. Rosenbaum
      Pages 165-176

    7. Echocardiographic Assessment of the Mouse Heart and Aorta

      • Brian D. Hoit
      Pages 177-190

    8. In Vivo Invasive Hemodynamic Studies in Mice

      • Brian D. Hoit
      Pages 191-205

    9. Pressure-Volume Relations

      • Dimitrios Georgakopoulos, David A. Kass
      Pages 207-222

    10. Assessment of Left Ventricular Diastolic Function in Mice

      • Michael R. Zile, Anne Hauet, Elizabeth Hapke, Janet Simsic
      Pages 223-236

    11. In Vivo Electrophysiologic Studies in Mice

      • Charles I. Berul, Paul J. Wang
      Pages 237-256

    12. Cardiovascular Physiology in Mice: Conscious Measurements and Effects of Anesthesia

      • Stephen F. Vatner, Gen Takagi, Kuniya Asai, Richard P. Shannon
      Pages 257-275

    13. Exercise and Oxygen Consumption in the Mouse

      • Kavin H. Desai, Daniel Bernstein
      Pages 277-302

    14. Clinical Laboratory Analysis of the Genetically Manipulated Mouse

      • William Lewis
      Pages 303-317
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Keywords

About this book

The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice. It is the primary objective of this second edition to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for the investigator interested in the functional methods used to characterize the murine cardiovascular phenotype. However, this guidebook is a more comprehensive text than its predecessor; although the major objectives enumerated in the first edition have not substantially changed, they have been refined in keeping with the increased sophistication of the molecular biologist, geneticist, and physiologist in each other's discipline. Each chapter has been expanded and updated, richly enhanced with original tables and figures, and in many cases, extensively rewritten. Eight chapters written by internationally recognized experts have been added; this represents a 43 % increase from the first edition.

Editors and Affiliations

  • Case Western Reserve University and University Hospitals of Cleveland, USA

    Brian D. Hoit, Richard A. Walsh

Bibliographic Information

  • Book Title: Cardiovascular Physiology in the Genetically Engineered Mouse

  • Editors: Brian D. Hoit, Richard A. Walsh

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4615-1653-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-0-7923-7536-4Published: 31 October 2001

  • Softcover ISBN: 978-1-4613-5661-5Published: 16 December 2012

  • eBook ISBN: 978-1-4615-1653-8Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 2

  • Number of Pages: XIV, 403

  • Topics: Biochemistry, general, Animal Physiology, Human Genetics, Cardiology

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