Skip to main content
SpringerLink
Log in
Book cover

Molecular Biology of Acute Lung Injury

  • Book
  • © 2001

Overview

Editors:
  1. Hector R. Wong

    1. Division of Critical Care Medicine, Children’s Hospital Medical Center and Children’s Hospital Research Foundation, Cincinnati, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Thomas P. Shanley

    1. Division of Critical Care Medicine, Children’s Hospital Medical Center and Children’s Hospital Research Foundation, Cincinnati, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Molecular & Cellular Biology of Critical Care Medicine (MCCM, volume 1)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Signal Transduction Pathways in Acute Lung Injury: Nf-κB and Ap-1

    • Thomas P. Shanley, Hector R. Wong
    Pages 1-16

  3. Innate Immune Mechanisms Triggering Lung Injury

    • Robert M. Strieter, John A. Belperio, David Kelley, Ammar Sakkour, Michael P. Keane
    Pages 17-33

  4. The Role of Chemokines in the Recruitment of Leukocytes During Lung Inflammation

    • Robert M. Strieter, John A. Belperio, David Kelley, Ammar Sakkour, Michael P. Keane
    Pages 35-51

  5. Regulation of Lung Immunity: Significance of the Cytokine Environment

    • Nicholas W. Lukacs, Theodore Standiford, Cory Hogaboam, Steven L. Kunkel
    Pages 53-69

  6. Role of Complement in Acute Lung Injury

    • Markus S. Huber-Lang, Peter A. Ward
    Pages 71-81

  7. Oxidant Stress in Acute Lung Injury

    • Jerry J. Zimmerman
    Pages 83-99

  8. Endogenous Nitric Oxide in Acute Lung Injury

    • Neil W. Kooy
    Pages 101-117

  9. Heme Oxygenase-1 in Acute Lung Injury

    • Jigme M. Sethi, Augustine M. K. Choi
    Pages 119-132

  10. Pulmonary Endothelial Surface Redox Activity: Roles in Propagation of and Protection from Injury

    • Marilyn P. Merker, Robert D. Bongard, Christopher A. Dawson
    Pages 133-148

  11. Mechanisms of Lung Epithelial Cell Injury by Pseudomonas Aeruginosa

    • Jeanine P. Wiener-Kronish, Dara Frank, Teiji Sawa
    Pages 149-161

  12. Alveolar Epithelial Repair in Acute Lung Injury

    • Thomas K. Geiser, Michael A. Matthay
    Pages 163-176

  13. Molecular Basis for Surfactant Function in ARDS

    • Liqian Zhang, Jeffrey A. Whitsett
    Pages 177-191

  14. Pulmonary Collectins and Defensins

    • Ann Marie LeVine
    Pages 193-211

  15. Lung Repair, Remodeling, and Fibrosis

    • Sujata Guharoy, Sem H. Phan
    Pages 213-227

  16. Apoptosis in Acute Lung Injury

    • Karine Faure, Benoit Guery, Jean Francois Pittet
    Pages 229-244

  17. Corticosteroid Treatment in Unresolving ARDS

    • G. Umberto Meduri
    Pages 245-256

  18. Anti-Inflammatory Cytokines: Role in Regulation of Acute Lung Injury

    • Thomas P. Shanley
    Pages 257-273

  19. The Heat Shock Response and Heat Shock Protein 70: Cytoprotection in Acute Lung Injury

    • Hector R. Wong
    Pages 275-288

  20. Biotrauma: Signal Transduction and Gene Expression in the Lung

    • Claudia C. dos Santos, Mingyao Liu, Arthur S. Slutsky
    Pages 289-325
Back to top

Keywords

About this book

Acute lung injury (ALI) impacts patient care in every ICU in the world. Our collective understanding of this condition has grown immensely over the past decade but morbidity and mortality remain unacceptably high. To enhance the understanding of clinicians and researchers, this book addresses the pathophysiology of acute lung injury from a molecular and cellular standpoint; includes animal models of acute lung injury and points to potential therapeutic advances based on scientific findings. It is a concise compendium of the multiple pathways, mechanisms and molecules involved in the pathophysiology of acute lung injury and is intended to help caregivers understand the process and thus care for patients more effectively.

Editors and Affiliations

  • Division of Critical Care Medicine, Children’s Hospital Medical Center and Children’s Hospital Research Foundation, Cincinnati, USA

    Hector R. Wong, Thomas P. Shanley

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation