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Frontiers in Modeling and Control of Breathing

Integration at Molecular, Cellular, and Systems Levels

  • Book
  • © 2001

Overview

Editors:
  1. Chi-Sang Poon

    1. Massachusetts Institute of Technology, Cambridge, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Homayoun Kazemi

    1. Massachusetts General Hospital and Harvard Medical School, Boston, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 499)

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Table of contents (80 chapters)

  1. Front Matter

    Pages i-xix
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  2. Oxford Conference: The Past, Present and Future

    1. Front Matter

      Pages 1-1
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    2. Remembrance of “Oxford” Conferences Past

      • Brian J. Whipp
      Pages 3-7

    3. Workshop on Modeling in the 21st Century

      • Chi-Sang Poon, Homayoun Kazemi
      Pages 9-14

  3. Central and Peripheral Chemoreceptors

    1. Front Matter

      Pages 15-15
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    2. Central Respiratory Chemosensitivity: Cellular and Network Mechanisms

      • David Ballantyne, Peter Scheid
      Pages 17-26

    3. Chemoreception and Tonic Drive in the Retrotrapezoid Nucleus (RTN) Region of the Awake Rat

      • Eugene E. Nattie
      Pages 27-32

    4. Chronic Intermittent Hypdxia Enhances Carotid Body Chemoreceptor Response to Low Oxygen

      • Y. Peng, D. D. Kline, T. E. Dick, N. R. Prabhakar
      Pages 33-38

    5. Neurotransmitter Release from the Rabbit Carotid Body: Differential Effects of Hypdxia on Substance P and Acetylcholine Release

      • Kim Dong-Kyu, Beth A. Summers, Nanduri R. Prabhakar, Ganesh K. Kumar
      Pages 39-43

    6. Muscarinic Receptors Influence Catecholamine Release from the Cat Carotid Body During Hypdxia

      • Hay-Yan J. Wang, Robert S. Fitzgerald
      Pages 45-48

    7. Pharmacological and Immunochemical Evidence of the Dopamine D3 Receptor in the Goat Carotid Body

      • Zun-Yi Wang, Jay K. Herman, Ken D. O’Halloran, Ingegerd M. Keith, Gerald E. Bisgard
      Pages 49-53

    8. The Excitatory Effect of Nitric Oxide on Carotid Body Chemoreception is Blocked by Oligomycin

      • Rodrigo Iturriaga, Matias Mosqueira
      Pages 55-60

    9. Co2/Hco3 - Modulates K+ and Ca2+ Currents in Glomus Cells of the Carotid Body

      • Jeffrey L. Overholt, Beth A. Summers, Eckhard Ficker, Nanduri R. Prabhakar
      Pages 61-66

    10. Inhibition or Lack of Nad(P)H Oxidase Subunits Do Not Alter the Normal Cytosolic Calcium, Sensory and Respiratory Response of Chemoreceptors

      • C. Rozanov, A. Roy, A. Mokashi, P. Daudu, C. Ross, S. Lahiri
      Pages 67-72

    11. Peripheral and Central Chemosensitivity: Multiple Mechanisms, Multiple Sites?

      • Eugene E. Nattie, Nanduri R. Prabhakar
      Pages 73-80

  4. Respiratory Neurons and Neural Networks

    1. Front Matter

      Pages 81-81
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    2. Role of Brainstem Respiratory Neuron Types in Phase-Switching Produced by Afferent Vagal Stimulation

      • Morton I. Cohen, Chen-Fu Shaw, Wu-Xin Huang, Qiping Yu
      Pages 83-88

    3. Modulation of the Central Respiratory Effects of 5-Ht by Vagal Afferents in Newborn Rat

      • Jean-Charles Glérant, Frédéric Salzmann, Josette Khater-Boidin, Bernard Duron
      Pages 89-93

    4. Activation of Medullary Post-Inspiratory Related Neurons During Clonidine-Induced Central Apnea in Anesthetized Goats

      • Ken D. O’Halloran, Jay K. Herman, Gerald E. Bisgard
      Pages 95-99

    5. Respiratory Control of Hypoglossal Motoneurons

      • John H. Peever, James Duffin
      Pages 101-106
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Keywords

About this book

The field of neural control of breathing has advanced rapidly in the past two decades, with the emergence of many new and promising research directions of increasing sophistication. The complexity and diversity of the current methodologies signify its remarkable vivacity, albeit at the price of much confusion. Captured in this book are the broad and intricate nature of the field and its multifaceted frontiers, including aspects of genetics, cell and molecular biology, comparative biology, neurophysiology, neurochemistry, neuroanatomy, imaging, human physiology in health and disease, and influence of environmental factors. Major topics include chemosensitivity, respiratory sensation, respiratory neurons, rhythmogenesis, plasticity, development, chemoreflex and exercise, respiratory instability and variability with behavioral and sleep states, etc., which are systematically laid out in the book for easy referencing.

Editors and Affiliations

  • Massachusetts Institute of Technology, Cambridge, USA

    Chi-Sang Poon

  • Massachusetts General Hospital and Harvard Medical School, Boston, USA

    Homayoun Kazemi

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