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Neurotoxic Factors in Parkinson’s Disease and Related Disorders

  • Book
  • © 2000

Overview

Editors:
  1. Alexander Storch

    1. University of Ulm Medical School, Ulm, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Michael A. Collins

    1. Loyola University Stritch School of Medicine, USA

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Table of contents (49 chapters)

  1. Front Matter

    Pages i-xv
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  2. Mechanisms of Selective Vulnerability

    1. Mechanisms of Selective Toxicity in Neurodegenerative Disorders

      • Peter S. Spencer
      Pages 1-16

    2. The Dopamine Transporter: Involvement in Selective Dopaminergic Neurodegeneration

      • Alexander Storch, Johannes Schwarz
      Pages 17-40

  3. MPTP/MPP+ Action and Mechanism

    1. Advances in our Knowledge of MPTP Action and Mechanism

      • Serge Przedborski
      Pages 41-53

    2. Role of Microtubules in the Genesis of MPTP Neurotoxicity

      • Graziella Cappelletti, M. Grazia Maggioni, Rosalba Maci
      Pages 55-58

    3. Complex I Inhibition in Cultured Cells as Model for Parkinson’s Disease

      • Rainer Ortmann, Andreas Hein, Stefan Frentzel
      Pages 59-63

    4. Nigral Degeneration in Animal Models of Multiple System Atrophy

      • Christoph Scherfler, Klaus Seppi, Zoe Puschban, Bernd Weiler, Harald Granbichler, Werner Poewe et al.
      Pages 65-68

  4. Isoquinolines as Potential Neurotoxins

    1. Isoquinoline Neurotoxins

      • Toshiharu Nagatsu
      Pages 69-76

    2. Apoptosis by an Endogenous Neurotoxin, N-Methyl(R)Salsolinol: Relevance to Parkinson’s Disease

      • Makoto Naoi, Wakako Maruyama, Yukihiko Akako, Yoshihito Nakagawa, Tsutomu Takahashi
      Pages 77-89

    3. Isoquinolines in Parkinson’s Disease

      • Shigeru Ohta
      Pages 91-100

    4. Systematic Studies of Dopamine and Dopamine-Derived Salsolinol and Norsalsolinol levels in Various Human Brain Areas

      • Frank Musshoff, Peter Schmidt, Reinhard Dettmeyer, Fritz Priemer, Holger Wittig, Bukhard Madea
      Pages 101-104

    5. Antidopaminergic Effects of Putative Endogenous MPTP-Like Agents: 1,2,3,4-Tetrahydroisoquinoline and 1-Methyl-6,7-Dihydroxy-l,2,3,4-Tetrahydroisoquinoline

      • Lucyna Antkiewicz-Michaluk, Irena Romanska, Jerzy Michaluk
      Pages 105-110

    6. Development of an HPLC-Method and Synthesis of 1,2,3,4-Tetrahydroisoquinolines as Reference Compounds for the Identification of Possible Neurotoxins in the Blood of Parkinson’s Disease Patients

      • Peter Pagel, Rainer Schubert, Christoph Wilhelm, Hans-Uwe Wolf
      Pages 111-114

  5. ß-Carbolines as Potential Neurotoxins

    1. ß-Carboline Analogues of MPP+ as Environmental Neurotoxins

      • Michael A. Collins, Edward J. Neafsey
      Pages 115-130

  6. ß-Carbolines as Potential Neurotoxins

    1. N-Methyl-ß-Carbolinium Neurotoxins in Parkinson’s Disease

      • Kazuo Matsubara
      Pages 131-143

    2. ‘TaClo’, A Chloral-Derived Mammalian Alkaloid with Neurotoxic Properties

      • Gerhard Bringmann, Ralph Brückner, Miriam Münchbach, Doris Feineis, Ralf God, Wolfgang Wesemann et al.
      Pages 145-149

    3. Nutritional Sources of Novel Tetrahydro-ß-Carbolines

      • Stefanie Diem, Birgit Gutsche, Markus Herderich
      Pages 151-154

  7. Catecholamine-Oxidation Pathways in Neurotoxicity

    1. Endogenous Brain Catechol Thioethers in Dopaminergic Neurodegeneration

      • Thomas J. Montine, Ventkataraman Amarnath, Matthew J. Picklo, Kathrin R. Sidell, Jing Zhang, Doyle G. Graham
      Pages 155-166

    2. Catecholamine-Derived Aldehyde Neurotoxins

      • William J. Burke, Shu Wen Li, Catherine A. Schmitt, Daniel S. Zahm, Hyung D. Chung, Ann D. Conway et al.
      Pages 167-180

    3. Potential Roles of Accelerated Dopamine Oxidation, Altered Glutathione Metabolism, 5-S-Cysteinyl-Dopamine and its Oxidative Metabolites in the Pathogenesis of Parkinson’s Disease

      • Glenn Dryhurst, Xue-Ming Shen, Hong Li, Zhaoliang Yang, Jilin Han, Fu-Chou Cheng
      Pages 181-209
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Keywords

Editors and Affiliations

  • University of Ulm Medical School, Ulm, Germany

    Alexander Storch

  • Loyola University Stritch School of Medicine, USA

    Michael A. Collins

Bibliographic Information

  • Book Title: Neurotoxic Factors in Parkinson’s Disease and Related Disorders

  • Editors: Alexander Storch, Michael A. Collins

  • DOI: https://doi.org/10.1007/978-1-4615-1269-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2000

  • Hardcover ISBN: 978-0-306-46529-1Published: 31 January 2001

  • Softcover ISBN: 978-1-4613-5470-3Published: 26 October 2012

  • eBook ISBN: 978-1-4615-1269-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XV, 340

  • Topics: Internal Medicine, Epidemiology, Pharmacology/Toxicology, Neurosciences, Public Health

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