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  • © 2002

ATP and the Heart

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Part of the book series: Basic Science for the Cardiologist (BASC, volume 11)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xvi
  2. ATP: The Molecule

    1. Front Matter

      Pages 1-1
    2. ATP and the Heart: An Overview

      • Joanne S. Ingwall
      Pages 3-6
    3. The Basics

      • Joanne S. Ingwall
      Pages 7-20
    4. The Chemistry of the ATPase Reaction

      • Joanne S. Ingwall
      Pages 21-37
  3. ATP: Degradation Pathway and de novo Synthesis

    1. Front Matter

      Pages 53-53
    2. Degradation and Synthesis of ATP

      • Joanne S. Ingwall
      Pages 55-99
  4. ATP Utilizing Pathways

    1. Front Matter

      Pages 101-101
    2. The Work of Contraction: Myosin ATPase

      • Joanne S. Ingwall
      Pages 103-124
    3. The Work of Ion Movements

      • Joanne S. Ingwall
      Pages 125-137
  5. ATP Synthesizing Pathways

    1. Front Matter

      Pages 145-145
    2. ATP Synthesis Pathways: Oxidative Phosphorylation

      • Joanne S. Ingwall
      Pages 165-196
  6. ATP and the Heart

    1. Front Matter

      Pages 215-215
  7. Back Matter

    Pages 241-244

About this book

ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current understanding of the chemistry and biology of ATP specifically in the cardiomyocyte is presented. New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac proteins are either over expressed, deleted or harbor specific mutations.

This book provides a summary of the basic understanding and includes illustrations of why ATP and the Heart is important to both the clinician and scientist.

Authors and Affiliations

  • Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston

    Joanne S. Ingwall

  • Harvard Medical School, Boston

    Joanne S. Ingwall

Bibliographic Information

  • Book Title: ATP and the Heart

  • Authors: Joanne S. Ingwall

  • Series Title: Basic Science for the Cardiologist

  • DOI: https://doi.org/10.1007/978-1-4615-1093-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-1-4020-7093-8Published: 30 June 2002

  • Softcover ISBN: 978-1-4613-5391-1Published: 30 October 2012

  • eBook ISBN: 978-1-4615-1093-2Published: 06 December 2012

  • Series ISSN: 1566-0753

  • Edition Number: 1

  • Number of Pages: XVI, 244

  • Topics: Cardiology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access