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Cardiovascular Genomics: New Pathophysiological Concepts

Proceedings of the 2001 European Science Foundation Workshop in Maastricht

  • Conference proceedings
  • © 2002

Overview

Editors:
  1. Pieter A. Doevendans

    1. Academic Hospital Maastricht, Maastricht, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Stefan Kääb

    1. Klinikum Grosshadern, Munich, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 242)

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Table of contents (23 papers)

  1. Front Matter

    Pages i-xix
    Download chapter PDF

  2. Genomics and Clinical Cardiology: Hype or Hope?

    1. Genomics and Clinical Cardiology: Hype or Hope?

      • H. J. Wellens
      Pages 1-4

  3. Gene expression analysis

    1. Front Matter

      Pages 5-5
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    2. Salt-Sensitive Hypertension

      • B. C. Rossier, D. Firsov
      Pages 7-19

    3. Cardiovascular Proteomics: Effect of Hypoxic Conditions

      • C. Michiels, D. Mottet, E. Delaive, M. Dieu, J-F. Dierick, J. Remacle
      Pages 21-28

    4. Using Comparative Genome Analysis to Find Interaction Partners for Frataxin

      • M. A. Huynen
      Pages 29-40

  4. Genomics and pathophysiology of atherosclerosis

    1. Front Matter

      Pages 41-41
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    2. In Vitro-In Vivo Gene Expression Analysis in Atherosclerosis

      • A. J. G. Horrevoets, R. J. Dekker, R. D. Fontijn, S. van Soest, H. Pannekoek
      Pages 43-52

  5. Genomics in hypertension

    1. Front Matter

      Pages 53-53
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    2. Human Essential Hypertension: Role of the Genes of the Renin-Aldosterone System

      • X. Jeunemaitre, S. Disse-Nicodème, A. Gimenez-Roqueplo, P. Corvol
      Pages 55-63

    3. Gene Therapy for Hypertension: Future or Fiction?

      • J. P. Fennell, M. J. Brosnan, A. J. Frater, A. H. Baker, A. F. Dominiczak
      Pages 65-75

    4. Hormones and Signalling Pathways

      • G. Lembo
      Pages 77-81

    5. Endothelial Changes in Hypertension

      • C. Zaragoza, S. Lamas
      Pages 83-94

  6. Genomics in cardiac hypertrophy and failure

    1. Front Matter

      Pages 95-95
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    2. Towards Elucidation of Genetic Pathways in Cardiac Hypertrophy: Technique to Develop Microarrays

      • B. J. C. van den Bosch, P. A. Doevendans, D. J. Lips, J. M. W. Geurts, H. J. M. Smeets
      Pages 97-105

    3. Gene Expression in Cardiac Hypertrophy and Failure: Role of G Protein-Coupled Receptors

      • G. Esposito, A. Rapacciuolo, S. V. Naga Prasad, H. A. Rockman
      Pages 107-114

    4. Little Mice with Big Hearts: Finding the Molecular Basis for Dilated Cardiomyopathy

      • L. J. De Windt, M. A. Sussman
      Pages 115-129

    5. Cardiac Hypertrophic Signaling the Good, the Bad and the Ugly

      • O. F. Bueno, E. van Rooij, D. J. Lips, P. A. Doevendans, L. J. De Windt
      Pages 131-156

  7. Molecular remodelling in arrhythmias

    1. Front Matter

      Pages 157-157
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    2. Ion Channel Regulation: From Arrhythmias to Genes to Channels (to Cures?)

      • J. K. Donahue
      Pages 159-165
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Keywords

About this book

Four years ago-in December 1997-the first European Science Foundation Workshop on Cardiovascular Specific Gene Expression was held in Maastricht. It was hardly possible to imagine the progress in the field in those four years. In 1997, gene expression was still an art focused on individual genes; in 200 I, many labs have access to micro-array facilities to determine the expression of thousands of genes simultaneously. In 1997, gene expression was an area of fundamental research in basis molecular biology laboratories; in 200 I, clinical cardiovascular research has incorporated gene expression approaches. In 1997, the interpretation of a gene expression experiment was usually straightforward; in 200 I, advanced bioinformatics tools are needed to approach the extreme complexities of genetic control of cell and tissue function. The second symposium in this series is focused on Cardiovascular Genomics. New Pathophysiological Concepts. The organizing committee chose to invite a group of renown scientists and young investigators around four topics of eminent importance in cardiovascular research. These topics reflect the major present-day clinical cardiovascular problems: atherosclerosis, hypertension, arrhythmias and heart failure. In addition to these four disease-driven topics, the workshop has sessions on gene expression methodologies and cellular transplant approaches to cardiovascular disease.

Editors and Affiliations

  • Academic Hospital Maastricht, Maastricht, Germany

    Pieter A. Doevendans

  • Klinikum Grosshadern, Munich, Germany

    Stefan Kääb

Bibliographic Information

  • Book Title: Cardiovascular Genomics: New Pathophysiological Concepts

  • Book Subtitle: Proceedings of the 2001 European Science Foundation Workshop in Maastricht

  • Editors: Pieter A. Doevendans, Stefan Kääb

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-1-4615-1005-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-1-4020-7022-8Published: 31 July 2002

  • Softcover ISBN: 978-1-4613-5347-8Published: 24 October 2012

  • eBook ISBN: 978-1-4615-1005-5Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XIX, 275

  • Topics: Cardiology, Human Genetics

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