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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3

Basic Science and Clinical Relevance Part B

  • Book
  • © 2002

Overview

Editors:
  1. David A. Sullivan

    1. Schepens Eye Research Institute, Boston, USA
      Harvard Medical School, Boston, USA

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  2. Michael E. Stern

    1. Allergan, Inc., Irvine, USA

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  3. Kazuo Tsubota

    1. Tokyo Dental College, Chiba, Japan
      Ichikawa General Hospital, Chiba, Japan

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  4. Darlene A. Dartt

    1. Schepens Eye Research Institute, Boston, USA
      Harvard Medical School, Boston, USA

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  5. Rose M. Sullivan

    1. Schepens Eye Research Institute, Boston, USA

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  6. B. Britt Bromberg

    1. University of New Orleans, New Orleans, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 506)

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Table of contents (196 chapters)

  1. Front Matter

    Pages i-xxvi
    Download chapter PDF

  2. Claes H. Dohlman Conference Address

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Understanding Dry Eye Syndrome

      • Kazuo Tsubota
      Pages 3-16

  3. Lacrimal Gland: Cellular and Molecular Biology

    1. Front Matter

      Pages 17-17
      Download chapter PDF

    2. GDNF Family Signalling in Exocrine Tissues: Distinct Roles for GDNF and Neurturin in Parasympathetic Neuron Development

      • Jari Rossi, Matti S. Airaksinen
      Pages 19-26

    3. The Influence of Aging in the Insulin-Signaling System in Rat Exocrine Glands

      • Eduardo M. Rocha, Carla R. O. Carvalho, Mário J. A. Saad, Lício A. Velloso
      Pages 27-31

    4. Cloning, Partial Sequencing and Expression of Rabbit Lacrimal Gland β-Hexosaminidase

      • J. Peter Gierow, Elsie C. Sjögren, Caroline Magnusson, Sven TÃ¥gerud
      Pages 33-39

    5. Differential Expression of Adenylyl Cyclase mRNAs in Lacrimal Glands of NZB/NZW and NOD Pre-Autoimmune Mice

      • Michele A. Meneray, Thomas E. Lallier
      Pages 41-49

    6. M3 Receptor Autoimmunity: Losing Tolerance to a Familiar Protein

      • Austin K. Mircheff, Limin Qian, Jiansong Xie, Yanru Wang, Sarah F. Hamm-Alvarez
      Pages 51-58

    7. Presence of α-and β-Integrin Subunits in Rabbit Lacrimal Gland Acinar Cells Cultured on a Laminin-Rich Matrix

      • J. Peter Gierow, Sofia Andersson, Elsie C. Sjögren
      Pages 59-63

    8. The Effects of Sensory and Parasympathetic Denervation on the Kinases and Initiation Factors Controlling Protein Synthesis in the Lacrimal Gland

      • Doan H. Nguyen, Roger W. Beuerman, Hiroshi Toshida
      Pages 65-70

    9. Familial Dysautonomia in Review: Diagnosis and Treatment of Ocular Manifestations

      • Cathleen A. Josaitis, Martin Matisoff
      Pages 71-80

    10. Somatostatin-Like Immunoreactivity (SLIR) in Rat Harderian and Meibomian Glands and Glands of Zeis

      • Mortimer Lorber
      Pages 81-89

    11. Neuronal Nitric Oxide Synthase is Expressed in the Mouse Lacrimal Gland and Neurons of Pterygopalatine Ganglion

      • Chuanqing Ding, Benjamin Walcott, Kent T. Keyser
      Pages 91-95

    12. Effects of Ageing on Secretagogue-Evoked Protein Output, Peroxidase Secretion and Protein Synthesis in the Isolated Rat Lacrimal Gland

      • Jaipaul Singh, Clare E. Draper, Ernest A. Adeghate
      Pages 97-101

    13. Effects of Ageing on Changes in Morphology of the Rat Lacrimal Gland

      • Ernest Adeghate, Claire E. Draper, Jaipaul Singh
      Pages 103-107

    14. The Role of Gap Junctions in Lacrimal Acinar Cells: The Formation of Tears

      • Peter R. Brink, Virginijus Valiunas, Leon Moore, Aija Birzgalis, Benjamin Walcott
      Pages 109-113

    15. Lipase mRNAs Expressed in Lacrimal and Harderian Glands

      • Susann G. Remington, J. Daniel Nelson
      Pages 115-119

    16. Gender-Related Differences in Gene Expression of the Lacrimal Gland

      • S. M. Richards, M. Liu, B. D. Sullivan, D. A. Sullivan
      Pages 121-127

    17. Identification of Androgen-Regulated Genes in the Lacrimal Gland

      • M. Liu, S. M. Richards, F. Schirra, H. Yamagami, B. D. Sullivan, D. A. Sullivan
      Pages 129-135
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Keywords

About this book

During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.

Editors and Affiliations

  • Schepens Eye Research Institute, Boston, USA

    David A. Sullivan, Darlene A. Dartt, Rose M. Sullivan

  • Harvard Medical School, Boston, USA

    David A. Sullivan, Darlene A. Dartt

  • Allergan, Inc., Irvine, USA

    Michael E. Stern

  • Tokyo Dental College, Chiba, Japan

    Kazuo Tsubota

  • Ichikawa General Hospital, Chiba, Japan

    Kazuo Tsubota

  • University of New Orleans, New Orleans, USA

    B. Britt Bromberg

Bibliographic Information

  • Book Title: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3

  • Book Subtitle: Basic Science and Clinical Relevance Part B

  • Editors: David A. Sullivan, Michael E. Stern, Kazuo Tsubota, Darlene A. Dartt, Rose M. Sullivan, B. Britt Bromberg

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-0717-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2002

  • Hardcover ISBN: 978-0-306-47282-4Published: 31 January 2003

  • Softcover ISBN: 978-1-4613-5208-2Published: 12 December 2012

  • eBook ISBN: 978-1-4615-0717-8Published: 11 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXX, 1399

  • Number of Illustrations: 176 b/w illustrations, 26 illustrations in colour

  • Topics: Ophthalmology, Evolutionary Biology, Veterinary Medicine/Veterinary Science, Immunology

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