Overview
Summarizes current understand of the role of respiratory irritants in inducing and exacerbating asthma, rhinitis, and related conditions
Constitutes essential reading for researching investigating chemical irritants, physicians caring for patients with asthma and rhinitis, as well as their patients and family members
Explores the brain as a target organ for both allergic and irritant reactions
Includes supplementary material: sn.pub/extras
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Table of contents (12 chapters)
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Front Matter
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Back Matter
About this book
Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals.
This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances. Allergists, toxicologists, occupational and environmental physicians, and pulmonologists will find the materials particularly valuable. Patients and advocates for those with chemical intolerances will also find the book of interest.
Editors and Affiliations
Bibliographic Information
Book Title: The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions
Editors: William J. Meggs
DOI: https://doi.org/10.1007/978-1-4614-9044-9
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-4614-9043-2Published: 24 January 2014
Softcover ISBN: 978-1-4899-7949-0Published: 17 September 2016
eBook ISBN: 978-1-4614-9044-9Published: 24 January 2014
Edition Number: 1
Number of Pages: VI, 294
Number of Illustrations: 6 b/w illustrations, 18 illustrations in colour
Topics: Pharmacology/Toxicology, Medicine/Public Health, general, Immunology