Integrative Biology of Women’s Health

1. Front Matter

   Pages i-x

   PDF

2. Influence of Ovarian Hormones on Skeletal Muscle Contractility

   • Dawn A. Lowe, Sarah M. Greising

   Pages 1-15

3. Novel Findings in Bone Biology: Impact on Bone Health for Women

   • Susan A. Bloomfield, Corinne E. Metzger

   Pages 17-33

4. Estrogen Effects on Skeletal Muscle

   • Marybeth Brown

   Pages 35-51

5. The Contribution of Ovarian Hormones to the Cellular Regulation of Lipid Metabolism

   • Espen E. Spangenburg, Kathryn C. Jackson

   Pages 53-66

6. The Role of Estrogens in the Regulation of Peripheral Glucose Dynamics

   • Paige C. Geiger, Anisha A. Gupte

   Pages 67-86

7. The Impact of Estrogen Receptor α Expression in the Pathogenesis of the Metabolic Syndrome

   • Andrea L. Hevener, Brian G. Drew

   Pages 87-121

8. Metabolic Health in the Aging Female: Human Perspective

   • Alice S. Ryan

   Pages 123-139

9. Transitions Across a Lifetime: Unique Cardiovascular Physiology of Women and Relationship to Cardiovascular Disease Risk

   • Juliana M. Kling, Virginia M. Miller, Sharon L. Mulvagh

   Pages 141-155

10. Estrogen, Cardiac Protection and Aging

    • Anne A. Knowlton

    Pages 157-174

11. Diet and Exercise Are Potent Modulators of Cardiovascular Disease in Women

    • Kristen K. B. Barthel, Pamela A. Harvey, Leslie A. Leinwand

    Pages 175-204

12. Back Matter

    Pages 205-212

    PDF

Defining and understanding cellular and molecular mechanisms that are relevant to women’s health has become a critical area of scientific pursuit. Until recently, very little effort has been place on defining or understanding critical differences between women and men that may be critical to the overall health of the woman. In 1990, the National Institutes of Health recognized this gap in knowledge resulting in the creation of the Office of Research on Women’s Health. One of the purposes of this office was to advance the understanding of health issues from the women’s perspective from both a basic and clinical scientific perspective. From a scientific evolution of understanding, the existence of this office is new and thus there has not been enough time for new information to integrate itself in our current scientific thought process. This book will seek to capture and disseminate our current understanding of scientific advancements relevant to women’s health and provide the information to a broad audience. The purpose of this work is to discuss recent advancements in basic science across three areas of concern for women’s health. In addition, the book will provide “translational” chapters that attempt to place the basic science work in context within our current understanding of the human. Although it is well acknowledge that gender differences exist across organ function which translates into differences in whole body function, until recently little effort has been made to define basic mechanisms within various tissues within the woman. This work will focus on recent scientific findings that are relevant to women’s health and to provide novel and relevant information to interested scientists and clinicians.

• cardiovascular
• estrogen
• metabolic
• muscle
• sex steroids
• skeletal
• women
• Receptors

• Department of Kinesiology, University of Maryland School of Public Health, College Park, USA

  Espen E. Spangenburg

Policies and ethics