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Fundamentals of Chromatin

  • Book
  • © 2014

Overview

Editors:
  1. Jerry L. Workman

    1. Stowers Institute for Medical Research, Kansas City, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Susan M. Abmayr

    1. Stowers Institute for Medical Research, Kansas City, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Focuses on fundamental properties of chromatin that include structure, composition, modifications and functions in nuclear processes such as transcription, and DNA replication and repair

  • Chapters from this book have been written by leading researchers in the field

  • This book provides an updated overview of the basics to knowing the function of chromatin

  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Histone, Nucleosome, and Chromatin Structure

    • Robert K. McGinty, Song Tan
    Pages 1-28

  3. Histone Chaperones in the Assembly and Disassembly of Chromatin

    • Briana K. Dennehey, Jessica Tyler
    Pages 29-67

  4. Chromatin Remodeling Complexes

    • Cedric R. Clapier, Bradley R. Cairns
    Pages 69-146

  5. Regulating Chromatin by Histone Acetylation

    • Anne-Lise Steunou, Dorine Rossetto, Jacques Côté
    Pages 147-212

  6. Histone Methylation in Chromatin Signaling

    • Or Gozani, Yang Shi
    Pages 213-256

  7. Histone Ubiquitylation Control of Gene Expression

    • Vikki M. Weake
    Pages 257-307

  8. Regulation of Chromatin Structure and Function by PARP-1 and ADP-Ribosylation

    • Ziying Liu, W. Lee Kraus
    Pages 309-339

  9. Histone Phosphorylation and Chromatin Dynamics

    • Mizusaki Hirofumi, Hitoshi Aihara, Takashi Ito
    Pages 341-354

  10. Reading Histone Modifications

    • Chun Ruan, Bing Li
    Pages 355-373

  11. Properties and Functions of Histone Variants

    • Emmanuelle Szenker, Ekaterina Boyarchuk, Geneviève Almouzni
    Pages 375-426

  12. Transcription Through Chromatin

    • Michaela Smolle, Swaminathan Venkatesh
    Pages 427-489

  13. Chromatin Remodeling in DNA Repair and Replication

    • Prabodh Kapoor, Xuetong Shen
    Pages 491-527

  14. Heterochromatin: A Critical Part of the Genome

    • Lori L. Wallrath, Michael W. Vitalini, Sarah C. R. Elgin
    Pages 529-552

  15. Emerging Areas of Chromatin Research

    • Tamaki Suganuma
    Pages 553-571

  16. Back Matter

    Pages 573-587
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Keywords

About this book

​​​​​​​​​​​​​While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. ​Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication.  The audience for this book is mainly newly established scientists ​and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.  

Editors and Affiliations

  • Stowers Institute for Medical Research, Kansas City, USA

    Jerry L. Workman, Susan M. Abmayr

Bibliographic Information

  • Book Title: Fundamentals of Chromatin

  • Editors: Jerry L. Workman, Susan M. Abmayr

  • DOI: https://doi.org/10.1007/978-1-4614-8624-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4614-8623-7Published: 04 December 2013

  • Softcover ISBN: 978-1-4939-4526-9Published: 23 August 2016

  • eBook ISBN: 978-1-4614-8624-4Published: 04 December 2013

  • Edition Number: 1

  • Number of Pages: XIII, 587

  • Number of Illustrations: 4 b/w illustrations, 94 illustrations in colour

  • Topics: Human Genetics, Biomedicine general, Gene Expression

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