Bronchiolitis Obliterans Syndrome in Lung Transplantation

1. Front Matter

   Pages i-xv

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2. Bronchiolitis Obliterans Syndrome and Chronic Lung Allograft Dysfunction: Evolving Concepts and Nomenclature

   • Keith C. Meyer, Allan R. Glanville

   Pages 1-19

3. Airway Pathology in Lung Transplants

   • Amir Lagstein, Jeffrey Myers

   Pages 21-46

4. Non-Bronchiolitis Obliterans Syndrome Forms of Chronic Lung Allograft Dysfunction

   • Gregory I. Snell, Bronwyn J. Levvey, Glen P. Westall

   Pages 47-58

5. The Role of Thoracic Imaging in the Diagnosis of BOS and Related Disorders

   • Jeffrey P. Kanne

   Pages 59-70

6. Making a Confident Diagnosis of Obliterative Bronchiolitis

   • A. Whitney Brown, Steven D. Nathan

   Pages 71-90

7. The Role of Alloimmune T Cell Responses in Obliterative Bronchiolitis

   • Tereza Martinu

   Pages 91-128

8. Antibody-Mediated Rejection and the Bronchiolitis Obliterans Syndrome

   • Henry W. Ainge-Allen, Allan R. Glanville

   Pages 129-145

9. Innate Immune Responses and Bronchiolitis Obliterans Syndrome

   • Jamie L. Todd, Scott M. Palmer

   Pages 147-167

10. Mechanisms of Fibrogenesis in Post-transplant Bronchiolitis Obliterans

    • Anish Wadhwa, Vibha N. Lama

    Pages 169-182

11. The Role of Autoimmunity in the Pathogenesis of Obliterative Bronchiolitis

    • Rudolf K. Braun, Keith C. Meyer, William J. Burlingham

    Pages 183-198

12. The Role of Infections in BOS

    • Robin K. Avery

    Pages 199-218

13. Gastroesophageal Reflux and Aspiration in Chronic Lung Allograft Dysfunction and Bronchiolitis Obliterans Syndrome: Detection and Treatment

    • Frank D’Ovidio, Beatrice Aramini

    Pages 219-235

14. Bronchiolitis Obliterans Syndrome in Children

    • Paul D. Robinson, Paul Aurora

    Pages 237-250

15. Immunosuppression for the Prevention and Treatment of BOS

    • Sangeeta M. Bhorade

    Pages 251-276

16. Macrolides for the Treatment and Prevention of BOS

    • Robin Vos, Stijn E. Verleden, David Ruttens, Bart M. Vanaudenaerde, Geert M. Verleden

    Pages 277-295

17. Other Treatments for Bronchiolitis Obliterans Syndrome

    • Ramsey Hachem

    Pages 297-311

18. Back Matter

    Pages 313-321

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Bronchiolitis Obliterans Syndrome in Lung Transplantation presents the most current and up-to-date evidence regarding the diagnosis and management of BOS.  In-depth chapters provide readers with a comprehensive understanding of the definition and changing perceptions of the nature of BOS as a clinical and pathologic entity, immune and non-immune mechanisms that have been identified as risk factors for the development of BOS, and interventions that may prove to be clinically useful for the prevention or treatment of BOS.  In addition to outlining the current state of knowledge, each chapter provides the reader with the most current and ongoing research in the field as well as identifies areas where future research is needed. Written by an international group of expert authors, Bronchiolitis Obliterans Syndrome in Lung Transplantation is an important new text, that is essential reading for pulmonologists, primary care practitioners, respiratory care practitioners and clinical researchers.

• bronchiolitis obliterans syndrome
• delayed allograft dysfunction
• lung allograft rejection
• lung transplantation
• obliterative bronchiolitis

From the reviews:

“This is a contemporary summary and review of the diagnostic parameters, biological processes, and treatment approaches for chronic lung transplant rejection. … this book provides worthwhile and useful resources for trainees, practitioners, and researchers in lung transplantation. Pulmonary specialists and general practitioners who refer or care for transplant recipients also will find this book helpful. … This is an up-to-date and comprehensive, in-depth, contemporary review of the complex factors that lead to chronic rejection following lung transplantation.” (Derek E. Byers, Doody’s Book Reviews, October, 2013)

• School of Medicine & Public Health, Dept. Internal Medicine, Sect. Allergy, University of Wisconsin, Madison, USA

  Keith C. Meyer

• Lung Transplant Unit, St. Vincent's Hospital, Sydney, Australia

  Allan R. Glanville

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