Hepatitis E Virus

1. Front Matter

   Pages i-vi

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2. Introduction

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 1-2

3. Etiology

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 3-10

4. Epidemiology of the Human HEV Infection

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 11-21

5. Pathogenesis in Humans

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 23-27

6. Epidemiology of HEV Infection in Animals

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 29-47

7. Pathogenesis in Swine

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 49-52

8. Diagnosis of Hepatitis E Infection

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 53-59

9. Hepatitis E Virus: Food Related Issues

   • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

   Pages 61-65

10. Conclusions

    • Franco Maria Ruggeri, Ilaria Di Bartolo, Fabio Ostanello, Marcello Trevisani

    Pages 67-68

11. Back Matter

    Pages 69-88

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Hepatitis E (HEV) is a viral infectious disease that infects humans and domestic, wild, and synanthropic animals alike. In developing countries, the disease often presents as an epidemic, transmitted primarily through the fecal-oral route. In recent years, sporadic cases have also been documented in industrial countries, including Europe. ​The identification and characterization of animal strains of HEV from pigs, wild boar, and deer, and the demonstrated ability of cross-species infection by these animal strains raise potential public health concerns for foodborne and zoonotic transmission of the virus. This Brief will provide a thorough overview of HEV. It will discuss the epidemiology and pathogenesis of the virus in both humans and animals, review detection methods, and provide methods for its control and prevention.

• Hepatitis E
• foodborne pathogen
• zoonotic diseases
• infectious diseases

• , Dept Vet. Public Health & Food Safety, Istituto Superiore di Sanità, Rome, Italy

  Franco Maria Ruggeri

• , Dept Food Safety & Veterinary Pub Health, Istituto Superiore di Sanità, Rome, Italy

  Ilaria Di Bartolo

• , Dept of Veterinary Medical Sciences, Bologna University, Bologna, Italy

  Fabio Ostanello

• Università di Bologna, Bologna, Italy

  Marcello Trevisani

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