A Case Approach to Perioperative Drug-Drug Interactions

The occurrence of deleterious or even fatal drug-drug interactions (DDIs) in the perioperative period is no longer a theoretical concern but a harrowing reality. A Case Approach to Perioperative Drug-Drug Interactions addresses the complex realm of pharmacokinetic drug interactions in an easy-to-read volume that functions as both a comprehensive clinical reference and a casebook.  The book presents a summary of the core concepts of drug interactions; an organized, annotated presentation of the drug interactions most relevant to the perioperative clinician; and approximately 200 case scenarios that highlight specific drug interactions. This book fills a real void in the clinical literature and is invaluable to anesthesiologists and surgeons, as well as trainees  in both specialties; intensive care staff, including physicians, physician’s assistants, and nurses; and nurse practitioners who staff preoperative evaluation clinics. 

• DDIs
• P450 system
• anesthesia
• case
• drug-drug interactions
• fatal drug interactions
• intensive care
• pain medicine
• patient safety
• perioperative medicine
• quality improvement

• Anesthesia Services Department, Philadelphia Veterans Affairs Med Center, Philadelphia, USA

  Catherine Marcucci

• Department of Anesthesiology, Oregon Health and Science University, Portland, USA

  Michael P. Hutchens

• Department of Anesthesiology, Mayo Clinic, Rochester, USA

  Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung, Wayne T. Nicholson

• Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, USA

  Kirk Lalwani

• Department of Anesthesiology, University of Pittsburgh School of Med Liliane S. Kaufmann Building, Pittsburgh, USA

  David G. Metro

• Department of Anesthesiology, University of Illinois at Chicago, Chicago, USA

  Randal O. Dull

• Department of Anesthesiology, Perioperative Medicine, Oregon Health and Science University, Portland, USA

  Christopher E. Swide

• Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, USA

  F. Jacob Seagull

• Department of Anesthesiology and Perioperative Medicine, Portland, USA

  Jeffrey R. Kirsch

• Department of Psychiatry, University of Maryland Medical System VA Maryland Health Care System, Baltimore, USA

  Neil B. Sandson

Catherine Marcucci, MD

Anesthesia Services Department

Philadelphia Veterans Affairs Medical Center

Philadelphia, PA, USA

Michael P. Hutchens, MD, MA

Department of Anesthesiology & Perioperative Medicine

Oregon Health & Science University                                              

Portland, OR, USA

Erica D. Wittwer, MD, PhD

Department of Anesthesiology

Mayo Clinic

Rochester, MN, USA

Toby N. Weingarten, MD

Department of Anesthesiology

Mayo Clinic

Rochester, MN, USA

Juraj Sprung, MD, PhD

Department of Anesthesiology

Mayo Clinic

Rochester, MN, USA

Wayne T. Nicholson, MD, PharmD, MSc

Department of Anesthesiology

Mayo Clinic

Rochester, MN, USA

Kirk Lalwani, MD, FRCA, MCR

Department of Anesthesiology & Perioperative Medicine

Oregon Health & Science University

Portland, OR, USA

David G. Metro, MD

Department of Anesthesiology

University of Pittsburgh School of Medicine

Pittsburgh, PA, USA

Randal O. Dull, MD, PhD

Department of Anesthesiology

University of Illinois at Chicago

Chicago, IL, USA

Christopher E. Swide, MD

Department of Anesthesiology & Perioperative Medicine

Oregon Health & Science University

Portland, OR, USA

F. Jacob Seagull, PhD

Department of Medical Education

University of Michigan Medical School

Ann Arbor, MI, USA       

Jeffrey R. Kirsch, MD

Department of Anesthesiology & Perioperative Medicine

Oregon Health & Science University

Portland, OR, USA

Neil B. Sandson, MD

Department of Psychiatry

University of Maryland Medical System

Department of Psychiatry

VA Maryland Health Care System

Baltimore, MD, USA

Policies and ethics