Overview
- Editors:
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Yuri B. Yurov
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Mental Health Research Center, Laboratory of Cytogenetics, Russian Academy of Medical Sciences, Moscow, Russia
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Svetlana G. Vorsanova
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Institute of Pediatry & Children Surgery, Laboratory of Molecular Cytogenetics of, Ministry of Health, Moscow, Russia
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Ivan Y. Iourov
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Mental Health Research Center, Laboratory of Molecular Brain Genetics, Russian Academy of Medical Sciences, Moscow, Russia
This is the first title to review modern achievements in the field of the post-genomic era’s genomics of interphase nuclei
Human Interphase Chromosomes play a significant role in a variety of basic biological processes involved in realization and inheritance of genetic information within and between species?
Provides special attention to available molecular cytogenetic technologies for basic and clinical chromosome research
Includes supplementary material: sn.pub/extras
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Table of contents (11 chapters)
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Front Matter
Pages i-xvii
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- Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov
Pages 1-8
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- Gemma Bourne, Catherine Moir, Ural Bikkul, Mai Hassan Ahmed, Ian R. Kill, Christopher H. Eskiw et al.
Pages 9-33
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- Gustavo A. Folle, MarÃa Vittoria Di Tomaso, Laura Lafon-Hughes, Pablo Liddle
Pages 35-51
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- Ivan Y. Iourov, Svetlana G. Vorsanova, Yuri B. Yurov
Pages 53-83
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- Joshua B. Stevens, Henry H. Q. Heng
Pages 85-105
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- Darren K. Griffin, Gothami Fonseka, Helen G. Tempest, Alan R. Thornhill, Dimitris Ioannou
Pages 123-138
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- Olga S. Mudrak, Liudmila V. Solovjeva, Vadim O. Chagin
Pages 139-159
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- Ivan Y. Iourov, Thomas Liehr, Svetlana G. Vorsanova, Yuri B. Yurov
Pages 161-169
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- Thomas Liehr, Hasmik Mkrtchyan, Marina Manvelyan, Tatyana Karamysheva, Elisabeth Klein, Samarth Bhatt
Pages 171-178
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- Svetlana G. Vorsanova, Yuri B. Yurov, Ivan Y. Iourov
Pages 179-203
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Back Matter
Pages 205-216
About this book
This title will focus on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and human genome function in interphase nuclei at the chromosomal level have been repeatedly shown to play a significant role in a variety of basic biological processes involved in realization and inheritance of genetic information within and between species. Current biomedical sciences of post-genomic era refocus basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease. Additionally, related processes are a target of studies elucidating the role of interphase chromosome behavior during development, chromosome/DNA replication, DNA reparation etc. Studies of interphase nuclei have an appreciable impact on different areas of biomedical sciences such as cell biology, neurobiology, cancer research, developmental biology, epigenetics, cytogenetics, and medical genetics, as a whole. Moreover, development of innovative and emergent technologies to analyze interphase nuclei are closely associated with application of these techniques in clinical, diagnostic and research practice to solve reproductive problems (including infertility and spontaneous abortions), to investigate congenital malformations (including those produced by aneuploidy and other chromosome abnormalities); genetic diseases (including cardiac, immune, neurological and psychiatric diseases), and cancer. This title will serve as a source of new valuable information and promising ideas for a wide audience of professionals in biomedicine including researchers, scientists, and healthcare professionals in human genetics, cytogenetics, and developmental biology. ​
Editors and Affiliations
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Mental Health Research Center, Laboratory of Cytogenetics, Russian Academy of Medical Sciences, Moscow, Russia
Yuri B. Yurov
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Institute of Pediatry & Children Surgery, Laboratory of Molecular Cytogenetics of, Ministry of Health, Moscow, Russia
Svetlana G. Vorsanova
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Mental Health Research Center, Laboratory of Molecular Brain Genetics, Russian Academy of Medical Sciences, Moscow, Russia
Ivan Y. Iourov
About the editors
^400 publications.
Svetlana G. Vorsanova (PhD, Dr. Sci, professor) is a head of laboratory of molecular cy^600 publications.
Yuri B. Yurov (PhD, Dr. Sci, professor; 1951-2017) was a pioneer of interphase molecular cytogenetics. He was the founding editor of Molecular Cytogenetics (BMC/Springer/Nature). He has (co-)authored >650 publications, including descriptions of groundbreaking studies in molecular cytogenetics of the human brain.
