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Androgen-Responsive Genes in Prostate Cancer

Regulation, Function and Clinical Applications

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  • © 2013

Overview

  • Focuses on androgen-responsive genes and prostate cancer, whereas other books have focused on androgen action and androgen receptors

  • Covers androgen-responsive genes in relation to carcinogenesis, cell growth, angiogenesis and more

  • Explores new approaches to diagnosis, prevention and treatment through understanding the mechanisms of androgen-responsive genes at the cellular level?

  • Includes supplementary material: sn.pub/extras

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Table of contents (20 chapters)

Keywords

About this book

Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males.  AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes.  Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action and may lead to new approaches in diagnosis, prognosis, prevention and/or treatment of prostate cancer.   This volume provides critical information from  well respected experts in the field.  Some of the exciting topics include the new understanding of mechanisms underlining the regulation of androgen-responsive gene expression, and functions of various androgen-responsive genes in biological processes essential in carcinogenesis including cell growth, angiogenesis, and epithelial-to-mesenchyme transition (EMT).  Other important aspects addressed are the current and potential clinic applications of knowledge on androgen-responsive gene regulation and function.  This book is intended for researchers, scientists, faculty, and advanced graduate students  with an interest in androgen action and prostate cancer.​  

Editors and Affiliations

  • , Shadyside Medical Center, University of Pittsburgh, Pittsburgh, USA

    Zhou Wang

About the editor

The volume editor, Dr. Zhou Wang, is well-noted in the field of prostate cancer and he is theChair for Urological Research at the University of Pittsburgh Medical Center, as well as the co-director of Urological and Prostate Cancer Program at the University of Pittsburgh Cancer Institute.He has also conducted several scientific reviews for several top journals in the area of cancer research.

Bibliographic Information

  • Book Title: Androgen-Responsive Genes in Prostate Cancer

  • Book Subtitle: Regulation, Function and Clinical Applications

  • Editors: Zhou Wang

  • DOI: https://doi.org/10.1007/978-1-4614-6182-1

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-4614-6181-4Published: 16 February 2013

  • Softcover ISBN: 978-1-4899-8687-0Published: 08 February 2015

  • eBook ISBN: 978-1-4614-6182-1Published: 16 February 2013

  • Edition Number: 1

  • Number of Pages: IX, 348

  • Number of Illustrations: 38 b/w illustrations, 37 illustrations in colour

  • Topics: Cancer Research, Gene Therapy, Human Genetics

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