Overview
- Editors:
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Zhou Wang
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, Shadyside Medical Center, University of Pittsburgh, Pittsburgh, USA
Focuses on androgen-responsive genes and prostate cancer, whereas other books have focused on androgen action and androgen receptors
Covers androgen-responsive genes in relation to carcinogenesis, cell growth, angiogenesis and more
Explores new approaches to diagnosis, prevention and treatment through understanding the mechanisms of androgen-responsive genes at the cellular level?
Includes supplementary material: sn.pub/extras
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Table of contents (20 chapters)
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- Irina U. Agoulnik, Nancy L. Weigel
Pages 1-11
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- Frank Claessens, Liesbeth Clinckemalie, Helsen Christine, Lien Spans, Vanessa Dubois, Michaël Laurent et al.
Pages 13-27
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- Benjamin Sunkel, Qianben Wang
Pages 43-58
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- Houtan Noushmehr, Simon G. Coetzee, Suhn K. Rhie, Chunli Yan, Gerhard A. Coetzee
Pages 59-84
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- Manohar Ratnam, Mugdha Patki, Mesfin Gonit, Robert Trumbly
Pages 85-100
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- Melanie L. Lehman, Colleen C. Nelson
Pages 117-134
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- Amy H. Tien, Marianne D. Sadar
Pages 135-153
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- Soo Ok Lee, Chiung-Kuei Huang, Luo Jie, Chawnshang Chang
Pages 155-176
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- Alfonso Urbanucci, Kati K. Waltering, Ian G. Mills, Tapio Visakorpi
Pages 187-200
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- Stephen R. Plymate, Jun Luo
Pages 201-213
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- Sarah K. Martin, Michael V. Fiandalo, Natasha Kyprianou
Pages 227-255
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- Alissa R. Verone, Hannelore V. Heemers
Pages 257-271
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- Laura E. Pascal, Zhou Wang
Pages 273-283
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- Judit Ribas, Shawn E. Lupold
Pages 285-305
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- Albert Dobi, Taduru Sreenath, Shiv Srivastava
Pages 307-328
About this book
Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males. AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes. Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action and may lead to new approaches in diagnosis, prognosis, prevention and/or treatment of prostate cancer.  This volume provides critical information from  well respected experts in the field. Some of the exciting topics include the new understanding of mechanisms underlining the regulation of androgen-responsive gene expression, and functions of various androgen-responsive genes in biological processes essential in carcinogenesis including cell growth, angiogenesis, and epithelial-to-mesenchyme transition (EMT). Other important aspects addressed are the current and potential clinic applications of knowledge on androgen-responsive gene regulation and function. This book is intended for researchers, scientists, faculty, and advanced graduate students with an interest in androgen action and prostate cancer.​ Â
Editors and Affiliations
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, Shadyside Medical Center, University of Pittsburgh, Pittsburgh, USA
Zhou Wang
About the editor
The volume editor, Dr. Zhou Wang, is well-noted in the field of prostate cancer and he is theChair for Urological Research at the University of Pittsburgh Medical Center, as well as the co-director of Urological and Prostate Cancer Program at the University of Pittsburgh Cancer Institute.He has also conducted several scientific reviews for several top journals in the area of cancer research.