Overview
- Provides an overview of whole cell modeling and its fundamental concepts
- Describes the Spatiocyte lattice-based simulation method which is developed as a set of E-Cell System plug in modules
- Provides examples of actual modeling applications that use the E-Cell System
Part of the book series: Molecular Biology Intelligence Unit (MBIU)
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Keywords
Table of contents (11 chapters)
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Applications
Authors and Affiliations
About the authors
Satya Arjunan is a Postdoctoral Researcher at the RIKEN Quantitative Biology Center, Japan. He received his PhD in Systems Biology from Keio University (2009), BEng in Electronics Engineering (2000) and MSc (2003) in Computer Science from Universiti Teknologi Malaysia. He is also the recipient of the Texas Instruments Malaysia Scholarship (1997) and the Monbukagakusho Scholarship (2003). As part of his PhD work, he developed a multicompartmental spatiotemporal stochastic simulation method, called Spatiocyte, with applications in molecular systems biology.
Pawan K. Dhar is the Director of the Centre of Systems and Synthetic Biology, University of Kerala. Prior to this he held senior scientific positions at RIKEN Genomics Sciences Centre, Japan, Bioinformatics Institute, Singapore and the E-Cell group, Keio University in Japan and Manipal University. One of his key recent contributions has been to make functional proteins from non‑coding genome. Dr. Dhar is the Founding Editor-in-Chief of the Springer's System and Synthetic Biology Journal. Dr. Dhar heads active research programs on synthetic proteins, virtual cell and BioCAD platform.
Masaru Tomita is a Professor and the Director General of the Institute for Advanced Biosciences, Keio University. He received PhD in Computer Science from Carnegie Mellon University (1985), PhD in Electrical Engineering from Kyoto University (1994) and PhD in Molecular Biology from Keio University (1998). He is a recipient of Presidential Young Investigators Award from National Science Foundation of USA (1988) and various other awards. His current research field includes Systems Biology, Metabolomics, and Computational Biology.
Bibliographic Information
Book Title: E‑Cell System
Book Subtitle: Basic Concepts and Applications
Authors: Satya Nanda Vel Arjunan, Pawan K. Dhar, Masaru Tomita
Series Title: Molecular Biology Intelligence Unit
DOI: https://doi.org/10.1007/978-1-4614-6157-9
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Landes Bioscience and Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-4614-6156-2Published: 25 January 2013
Softcover ISBN: 978-1-4939-4761-4Published: 23 August 2016
eBook ISBN: 978-1-4614-6157-9Published: 13 May 2013
Series ISSN: 1431-0414
Edition Number: 1
Number of Pages: XIV, 179
Topics: Molecular Medicine, Biomedicine general