Overview
- Will offer a new understanding of immunity to tuberculosis
- Explore a novel approach to designing a new tuberculosis vaccine
- Cover the latest advances in tuberculosis research of the past decade
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 783)
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Table of contents (14 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.
The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection.
Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.
Editors and Affiliations
Bibliographic Information
Book Title: The New Paradigm of Immunity to Tuberculosis
Editors: Maziar Divangahi
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4614-6111-1
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2013
Hardcover ISBN: 978-1-4614-6110-4Published: 07 March 2013
Softcover ISBN: 978-1-4899-9063-1Published: 20 April 2015
eBook ISBN: 978-1-4614-6111-1Published: 12 March 2013
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VI, 292
Topics: Immunology, Medical Microbiology, Antibodies, Vaccine