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  • © 2013

Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems

Authors:

  • Reviews structure and function of major constituents of the circulatory and respiratory apparatus
  • Describes major cellular processes involved in signaling, interactions, and adaptive responses of physiological conduits
  • Integrates biology, chemistry, and physics for the multidisciplinary exploration and modeling of physiological flows
  • Focuses on mechanotransduction-induced regulation
  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xxi
  2. Blood

    • Marc Thiriet
    Pages 1-18
  3. Hematopoiesis

    • Marc Thiriet
    Pages 19-52
  4. Blood Cells

    • Marc Thiriet
    Pages 53-175
  5. Lymph Drainage

    • Marc Thiriet
    Pages 177-187
  6. Cardiomyocytes

    • Marc Thiriet
    Pages 189-269
  7. Heart Wall

    • Marc Thiriet
    Pages 271-348
  8. Vessel Wall

    • Marc Thiriet
    Pages 349-380
  9. Smooth Myocytes

    • Marc Thiriet
    Pages 381-452
  10. Vascular Endothelium

    • Marc Thiriet
    Pages 453-603
  11. Vasculature Growth

    • Marc Thiriet
    Pages 605-673
  12. Tissue Development, Repair, and Remodeling

    • Marc Thiriet
    Pages 675-747
  13. Airway Surface Liquid and Respiratory Mucus

    • Marc Thiriet
    Pages 749-787
  14. Surfactant

    • Marc Thiriet
    Pages 789-804
  15. Conclusion

    • Marc Thiriet
    Pages 805-812
  16. Back Matter

    Pages 813-962

About this book

The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models.  The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.

Authors and Affiliations

  • Laboratoire Jacques-Louis Lions, Institut Universitaire de France, Université Pierre et Marie Curie, Paris, France

    Marc Thiriet

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access