Overview
- Includes supplementary material: sn.pub/extras
Part of the book series: SpringerBriefs in Stem Cells (BRIEFSSTEM)
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Table of contents (3 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This Brief offers a concise, handy overview of the main concepts related to Embryology, revisited through the novel concepts that are applied daily in stem cell research and cell therapy oriented investigations. It is based on three main areas:
-The process involved in female gamete differentiation and maturation. The main aspects related to cell biology will be covered and an overview of the epigenetic regulation of gametogenesis will be presented.
-Early stages of embryo development with a careful analysis of the regulatory mechanisms driving cleavage, polarization and genome activation.
-Stem cell and gametogenesis.
The use of the oocyte as a possible source for the derivation of stem cell lines is discussed and depicted as a powerful tool to investigate oocyte potency and asymmetric imprinting. The potential biological implications are evaluated and use of stem cells to derive oocytes is presented.
Authors and Affiliations
About the authors
Tiziana A.L Brevini is Associate Professor of Anatomy and Embryology at the University of Milan, Italy. She graduated in 1989 and spent three years at the Department of Molecular Embryology, Cambridge (UK). She obtained a PhD in 1994 and then carried out research programs at Monash University, Melbourne and at the University of Adelaide, Australia. Her main area of research is addressed to the understanding of cell differentiation process and pluripotency related networks in mammalian cells and embryos.
Georgia Pennarossa is lecturer at the University of Milan, Italy. Graduated in 2007, she obtained a PhD in Biotechnology in 2012. She has been actively involved in research for the last 5 years at the Unit of Biomedical Embryology, University of Milan, Italy. Her scientific interest is addressed to the understanding of the main aspects related to gametogenesis, embryo development and cell differentiation.
Bibliographic Information
Book Title: Gametogenesis, Early Embryo Development and Stem Cell Derivation
Authors: Tiziana A.L. Brevini, Georgia Pennarossa
Series Title: SpringerBriefs in Stem Cells
DOI: https://doi.org/10.1007/978-1-4614-5532-5
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Author(s) 2013
Softcover ISBN: 978-1-4614-5531-8Published: 30 September 2012
eBook ISBN: 978-1-4614-5532-5Published: 30 September 2012
Series ISSN: 2192-8118
Series E-ISSN: 2192-8126
Edition Number: 1
Number of Pages: XI, 66
Number of Illustrations: 32 b/w illustrations, 16 illustrations in colour
Topics: Stem Cells, Reproductive Medicine, Cell Biology