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Mechanisms and Emerging Therapies in Tremor Disorders

  • Book
  • © 2013

Overview

Editors:
  1. Giuliana Grimaldi

    1. , Unité d'Etude due Mouvement (UEM), Neurologie ULB Erasme, Bruxelles, Belgium

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    You can also search for this editor in PubMed   Google Scholar

  2. Mario Manto

    1. Bruxelles, Belgium

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Detailed description of the various forms of tremor encountered in humans
  • Covers recent advances in methodologies and techniques of assessment, and provides practical information for the daily management
  • Intended for a large audience of scientists, clinicians including neurologists and neurosurgeons, internists, fellows, trainees, biologists, biomedical and electrical engineers
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Clinical Neuroscience (CCNE)

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Fundamental Aspects

    1. Front Matter

      Pages 1-1
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  3. Fundamental aspects

    1. Definition of Tremor

      • Giuliana Grimaldi, Mario Manto
      Pages 3-10

    2. Membrane Mechanisms of Tremor

      • Aasef G. Shaikh, Lance M. Optican, David S. Zee
      Pages 11-35

    3. Rodent Models of Tremor

      • Hideto Miwa
      Pages 37-51

    4. Advances in the Genetics of Human Tremor

      • Fabio Coppedè
      Pages 53-78

    5. Musculoskeletal Models of Tremor

      • Dingguo Zhang, Wei Tech Ang
      Pages 79-107

  4. The Various Forms of Tremor in Clinical Practice: Presentation and Mechanisms

    1. Front Matter

      Pages 109-109
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  5. The various forms of tremor in clinical practice: presentation and mechanisms

    1. Physiologic Tremor

      • Rodger J. Elble
      Pages 111-119

    2. Rest Tremor

      • Giuliana Grimaldi, Mario Manto
      Pages 121-131

    3. Postural Tremors

      • Jean-François Daneault, Benoit Carignan, Fariborz Rahimi, Abbas F. Sadikot, Christian Duval
      Pages 133-150

    4. Isometric Tremor

      • Dennis A. Nowak, Hans-Jürgen Gdynia, Jan Raethjen
      Pages 151-166

    5. Essential Tremor and Other Forms of Kinetic Tremor

      • Elan D. Louis
      Pages 167-201

    6. Dystonic Tremor

      • Stefania Lalli, Alberto Albanese
      Pages 203-218

    7. Orthostatic Tremor

      • Julián Benito-León, Andrés Labiano-Fontcuberta, Elan D. Louis
      Pages 219-233

    8. Vocal Tremor

      • Katherine A. Kendall
      Pages 235-248

    9. Update in Familial Cortical Myoclonic Tremor with Epilepsy

      • Eloi Magnin, Pierre Labauge, Lucien Rumbach, Marie Vidailhet
      Pages 249-262

    10. Posttraumatic Tremor and Other Posttraumatic Movement Disorders

      • Jose Fidel Baizabal-Carvallo, Joseph Jankovic
      Pages 263-287

    11. Psychogenic Tremor

      • Luis Redondo-Vergé, Natividad Carrion-Mellado
      Pages 289-304

    12. Tremor in Childhood

      • Padraic J. Grattan-Smith, Russell C. Dale
      Pages 305-322
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About this book

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented.

Reviews

“This is an outstanding book concerning the timing mechanisms of resting, action, and hereditary aspects of dystonias, Parkinson’s disease, Multiple Sclerosis, etc. … I highly recommend this book for researchers and students at the beginning and experienced levels. Neurophysiologists, neurosurgeons, neurologists, and muscle physiologists will likely benefit from this atlas/text formats.” (Joseph J. Grenier, Amazon.com, June, 2015)

“This authoritative guide to the management and understanding of tremor disorders provides a holistic view of the multifactorial causes of tremor. … The book is written for all medical practitioners whether they are neurologists or not. … the book can easily be used by any health professional looking to bridge the clinical signs to the scientific underpinnings of cause and treatment. … it merits being available in all hospital libraries and it should be used often in helping patients with tremor disorders.” (Joseph I. Sirven, Doody’s Review Service, November, 2012)

Editors and Affiliations

  • , Unité d'Etude due Mouvement (UEM), Neurologie ULB Erasme, Bruxelles, Belgium

    Giuliana Grimaldi

  • Bruxelles, Belgium

    Mario Manto

Bibliographic Information

  • Book Title: Mechanisms and Emerging Therapies in Tremor Disorders

  • Editors: Giuliana Grimaldi, Mario Manto

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-1-4614-4027-7

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Softcover ISBN: 978-1-4899-9074-7Published: 19 September 2014

  • eBook ISBN: 978-1-4614-4027-7Published: 21 August 2012

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 1

  • Number of Pages: XVI, 492

  • Topics: Biomedicine general, Neurology

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