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  • © 2012

Evolutionary Systems Biology

Editors:

  • Highlights the diverse array of methodologies and approaches employed in evolutionary systems biology
  • This book tries to decipher “evolutionary design principles” and the origins of systems level properties in biology, such as modularity, robustness, and network connectivity
  • Includes comparative (genomics) analyses that aim to decipher diversity in specific molecular systems
  • Includes supplementary material: sn.pub/extras

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-x
  2. Metabolic Networks and Their Evolution

    • Andreas Wagner
    Pages 29-52
  3. Organization Principles in Genetic Interaction Networks

    • Christopher Jacobs, Daniel Segrè
    Pages 53-78
  4. Life’s Attractors

    • Johannes Jaeger, Anton Crombach
    Pages 93-119
  5. Evolutionary Characteristics of Bacterial Two-Component Systems

    • Xia Sheng, Maxime Huvet, John W. Pinney, Michael P. H. Stumpf
    Pages 121-137
  6. Comparative Interaction Networks: Bridging Genotype to Phenotype

    • Pedro Beltrao, Colm Ryan, Nevan J. Krogan
    Pages 139-156
  7. Reverse Ecology: From Systems to Environments and Back

    • Roie Levy, Elhanan Borenstein
    Pages 329-345
  8. Bacteria–Virus Coevolution

    • Angus Buckling, Michael Brockhurst
    Pages 347-370
  9. Building Synthetic Systems to Learn Nature’s Design Principles

    • Eric A. Davidson, Oliver P. F. Windram, Travis S. Bayer
    Pages 411-429

About this book

The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.

Editors and Affiliations

  • University of Exeter, Exeter, United Kingdom

    Orkun S. Soyer

Bibliographic Information

  • Book Title: Evolutionary Systems Biology

  • Editors: Orkun S. Soyer

  • DOI: https://doi.org/10.1007/978-1-4614-3567-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • Hardcover ISBN: 978-1-4614-3566-2Published: 21 July 2012

  • eBook ISBN: 978-1-4614-3567-9Published: 23 July 2012

  • Edition Number: 1

  • Number of Pages: X, 458

  • Topics: Systems Biology, Evolutionary Biology, Biomedicine general

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access