Overview
- Source of basic studies that range from biochemistry to molecular biology to receptor pharmacology and physiology
- Written by authors well known in the RAMPs field
- Provides information for scientists at different stages of their career including graduate students, post-doctoral fellows and senior scientists who are new to the RAMPs field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 744)
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Table of contents(9 chapters)
About this book
 Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions. Therefore, understanding how these receptors function is a critical question in the field. When Foord and his colleagues discovered that a single transmembrane protein called Receptor Activity Modifying Proteins (RAMPs) could modulate the surface expression of GPCRs of the calcitonin family, it widely opened the field of receptor life cycle. Hundreds of studies have confirmed the importance of RAMPs in the life cycle of this receptor family. Receptor biology is a rapidly expanding field and with the advances in cell and molecular biology and in vivo techniques, it is very likely that the field of RAMPs will explode further and many unanswered questions will be answered with in the next few years.
Editors and Affiliations
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Department of Physiology, Michigan State University, East Lansing, USA
William S. Spielman, Narayanan Parameswaran
About the editors
William S. Spielman is a Professor of Physiology and former Chairperson of the Department of Physiology, Michigan State University, East Lansing, Michigan, USA. His research interests include receptor biology and signal transduction and renal physiology. He is a member of many national and international scientific societies including the American Physiological Society. Spielman earned the BS degree in Biology from Westminister College and the PhD degree in Physiology from the University of Missouri.
Narayanan Parameswaran is an Associate Professor in the Department of Physiology and Division of Pathology at Michigan State University, East Lansing, Michigan, USA. His main research interests include receptor biology, cell signaling, inflammation and inflammatory diseases. He is a member of the American Association of Immunology, Society of Leukocyte Biology and the Shock Society. Parameswaran received the Veterinary Medicine degree from Madras Veterinary College (India), the Master’s degree in Veterinary Physiology and Pharmacology from the Ohio State University and the Doctor of Philosophy degree in Physiology from the Michigan State University.
Bibliographic Information
Book Title: RAMPs
Editors: William S. Spielman, Narayanan Parameswaran
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4614-2364-5
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012
Hardcover ISBN: 978-1-4614-2363-8Published: 14 February 2012
Softcover ISBN: 978-1-4939-5292-2Published: 23 August 2016
eBook ISBN: 978-1-4614-2364-5Published: 21 March 2012
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XVII, 114
Topics: Biomedicine general, Cell Biology, Molecular Medicine