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Genetics Meets Metabolomics

from Experiment to Systems Biology

  • Book
  • © 2012

Overview

Editors:
  1. Karsten Suhre

    1. Qatar Foundation-Education City, Weill Cornell Medical College in Qatar, Doha, Qatar

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  • Addresses a selected aspect of the genetic background to a metabolic phenotype

  • All chapters refer to one or more published experimental datasets

  • Looks at research about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Introduction

    • Karsten Suhre
    Pages 1-4

  3. Pre-conditions for High Quality Biobanking in Large Human Epidemiological Cohorts for Metabolomics and Other – Omics Studies

    • Thomas Illig
    Pages 5-11

  4. Assay Tools for Metabolomics

    • Anna Artati, Cornelia Prehn, Gabriele Möller, Jerzy Adamski
    Pages 13-38

  5. Statistical Methods in Genetic and Molecular Epidemiology and Their Application in Studies with Metabolic Phenotypes

    • Christian Gieger
    Pages 39-56

  6. Ultrahigh Resolution Mass Spectrometry Based Non-targeted Microbial Metabolomics

    • Michael Witting, Marianna Lucio, Dimitrios Tziotis, Philippe Schmitt-Kopplin
    Pages 57-71

  7. Metabolomic Systems Biology of Protozoan Parasites

    • Rainer Breitling, Barbara M. Bakker, Michael P. Barrett, Saskia Decuypere, Jean-Claude Dujardin
    Pages 73-84

  8. Mouse Genetics and Metabolic Mouse Phenotyping

    • Helmut Fuchs, Susanne Neschen, Jan Rozman, Birgit Rathkolb, Sibylle Wagner, Thure Adler et al.
    Pages 85-106

  9. Metabolomics in Animal Breeding

    • Christa Kühn
    Pages 107-123

  10. Metabolomics Applications in Human Nutrition

    • Hannelore Daniel, Manuela Sailer
    Pages 125-137

  11. Metabolomics for the Individualized Therapy of Androgen Deficiency Syndrome in Male Adults

    • Robin Haring, Kathrin Budde, Henri Wallaschofski
    Pages 139-155

  12. Systems Biology Resources Arising from the Human Metabolome Project

    • David Wishart
    Pages 157-175

  13. Understanding Cancer Metabolism Through Global Metabolomics

    • Michael V. Milburn, Kay A. Lawton, Jonathan E. McDunn, John A. Ryals, Lining Guo
    Pages 177-190

  14. Genetic and Metabolic Determinants of Fatty Acid Chain Length and Desaturation, Their Incorporation into Lipid Classes and Their Effects on Risk of Vascular and Metabolic Disease

    • Thomas Kopf, Markus Peer, Gerd Schmitz
    Pages 191-231

  15. Mapping Metabolomic Quantitative Trait Loci (mQTL): A Link Between Metabolome-Wide Association Studies and Systems Biology

    • Marc-Emmanuel Dumas, Dominique Gauguier
    Pages 233-254

  16. Metabolic Traits as Intermediate Phenotypes

    • Florian Kronenberg
    Pages 255-264

  17. Genome-Wide Association Studies with Metabolomics

    • Karsten Suhre
    Pages 265-279

  18. Systems Biology Meets Metabolism

    • Jan Krumsiek, Ferdinand Stückler, Gabi Kastenmüller, Fabian J. Theis
    Pages 281-313

  19. Back Matter

    Pages 315-318
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Keywords

About this book

This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

Editors and Affiliations

  • Qatar Foundation-Education City, Weill Cornell Medical College in Qatar, Doha, Qatar

    Karsten Suhre

Bibliographic Information

  • Book Title: Genetics Meets Metabolomics

  • Book Subtitle: from Experiment to Systems Biology

  • Editors: Karsten Suhre

  • DOI: https://doi.org/10.1007/978-1-4614-1689-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-1688-3Published: 02 July 2012

  • Softcover ISBN: 978-1-4899-9695-4Published: 17 July 2014

  • eBook ISBN: 978-1-4614-1689-0Published: 15 June 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 318

  • Topics: Human Genetics, Metabolomics, Systems Biology

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