20 Years of Computational Neuroscience

1. Front Matter

   Pages i-xiv

   PDF

2. Introduction: Origins and History of the CNS Meetings

   • John Miller, James M. Bower

   Pages 1-12

3. A Pictorial History of the Early Days of Computational Neuroscience: The CNS Meeting Posters

   • James M. Bower

   Pages 13-32

4. History of Neural Simulation Software

   • David Beeman

   Pages 33-71

5. Learning from the Past: Approaches for Reproducibility in Computational Neuroscience

   • Sharon M. Crook, Andrew P. Davison, Hans E. Plesser

   Pages 73-102

6. The Emergence of Community Models in Computational Neuroscience: The 40-Year History of the Cerebellar Purkinje Cell

   • James M. Bower

   Pages 103-140

7. Calcium: The Answer to Life, the Universe, and Everything

   • Kim Blackwell

   Pages 141-158

8. The More We Look, the More Biological Variation We See: How Has and Should This Influence Modeling of Small Networks?

   • Ronald L. Calabrese

   Pages 159-166

9. 20 Years of “Noise”: Contributions of Computational Neuroscience to the Exploration of the Effect of Background Activity on Central Neurons

   • Alain Destexhe

   Pages 167-186

10. Still Looking for the Memories: Molecules and Synaptic Plasticity

    • Upinder S. Bhalla

    Pages 187-205

11. 20 Years of the Dynamics of Memory: The Long and Winding Road Linking Cellular Mechanisms to Behavior

    • Michael E. Hasselmo

    Pages 207-227

12. Spatiotemporal Coding in the Olfactory System

    • Christiane Linster, Thomas A. Cleland

    Pages 229-242

13. 20 Years of Learning About Vision: Questions Answered, Questions Unanswered, and Questions Not Yet Asked

    • Bruno A. Olshausen

    Pages 243-270

14. Reinforcement Learning Models Then-and-Now: From Single Cells to Modern Neuroimaging

    • P. Read Montague

    Pages 271-277

15. Back Matter

    Pages 279-283

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When funding agencies and policy organizations consider the role of modeling and simulation in modern biology, the question is often posed, what has been accomplished ? This book will be organized around a symposium on the 20 year history of the CNS meetings, to be held as part of CNS 2010 in San Antonio Texas in July 2010. The book, like the symposium is intended to summarize progress made in Computational Neuroscience over the last 20 years while also considering current challenges in the field. As described in the table of contents, the chapter’s authors have been selected to provide wide coverage of the applications of computational techniques to a broad range of questions and model systems in neuroscience. The proposed book will include several features that establish the history of the field. For each article, its author will select an article originally appearing in a CNS conference proceedings from 15 – 20 years ago. These short (less than 6 page) articles will provide illustrations of the state of the field 20 years ago. The new articles will describe what has been learned about the subject in the following 20 years, and pose specific challenges for the next 20 years. The second historical mechanism will be the reproduction of the first 12 years of posters from the CNS meeting. These posters in and of themselves have become famous in the field (they hang in the halls of the NIH in Bethesda Maryland) and were constructed as allegories for the state and development of computational neuroscience. The posters were designed by the book’s editor, who will, for the first time, provide a written description of each poster.

• San Antonio, USA

  James M Bower

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