Editors:
- Written by leaders in their respective fields
- Uses the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance
- Conveys state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 726)
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Table of contents (28 chapters)
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Front Matter
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Viral Entry Machines
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Front Matter
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Genome Replication Machines
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Front Matter
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GENOME REPLICATION MACHINES
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Capsid Assembly and Maturation
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Front Matter
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About this book
This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion.
Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.
Editors and Affiliations
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Dept. Biological Sciences, Purdue University, West Lafayette, USA
Michael G. Rossmann
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Dept. Biology, Catholic University of America, Washington, USA
Venigalla B. Rao
Bibliographic Information
Book Title: Viral Molecular Machines
Editors: Michael G. Rossmann, Venigalla B. Rao
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4614-0980-9
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012
Hardcover ISBN: 978-1-4614-0979-3Published: 26 December 2011
Softcover ISBN: 978-1-4939-5085-0Published: 23 August 2016
eBook ISBN: 978-1-4614-0980-9Published: 02 February 2012
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIV, 687
Topics: Virology, Microbiology, Infectious Diseases, Immunology