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Cell Signaling & Molecular Targets in Cancer

  • Book
  • © 2012

Overview

Editors:
  1. Malay Chatterjee

    1. , Pharmaceutical Technology, Jadavpur University, Kolkata, India

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  2. Khosrow Kashfi

    1. , Division of Biochemistry & Chemistry, City University of New York Medical Scho, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Identifies various signaling molecules like GRB2 growth factors, A1B1, STAT, TGFß

  • Provides a critical assessment of surrogate markers involved in the emergence and progression of cancer

  • Covers the basic principle that drive oncogenesis and pharmacological interventions that lead to therapies

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xi
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  2. GRB2 Signaling as a Molecular Target for Cancer

    • Alessio Giubellino
    Pages 1-22

  3. Human Arylamine N-acetyltransferase 1: From Drug Metabolism to Drug Target

    • Fernando Rodrigues-Lima, Julien Dairou, Florent Busi, Jean-Marie Dupret
    Pages 23-35

  4. Targeting Argininosuccinate Synthetase in Cancer Therapy

    • Niramol Savaraj, Min You, Chunjing Wu, Macus Tien Kuo, Vy Dinh, Medhi Wangpaichitr et al.
    Pages 37-51

  5. Parathyroid Hormone–Related Peptide Signaling in Cancer

    • Franco Oreste Ranelletti, Giovanni Monego
    Pages 53-85

  6. Signalling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma

    • Francesco Piazza, Gianpietro Semenzato
    Pages 87-108

  7. Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract

    • Hiroshi Yasuda, Fumio Itoh
    Pages 109-128

  8. AIB1: A Transcriptional Coactivator Which Integrates Signaling Cross Talk in Cancer Cells

    • Macarena Ferrero, Jaime Font de Mora
    Pages 129-166

  9. Rational Design of DNA Anticancer Agent That Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy

    • Naijie Jing
    Pages 167-190

  10. Estrogen Receptor Signaling in Lung Cancer

    • P. A. Hershberger, J. M. Siegfried
    Pages 191-210

  11. Microparticle Dissemination of Biological Activities: Implications for Cancer Biology

    • Pauline P. Goh
    Pages 211-243

  12. Protein Kinase D Signaling in Cancer

    • Peter Storz
    Pages 245-271

  13. Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer, Reactive Oxygen Species, and Antioxidants

    • Peter Kovacic, Ratnasamy Somanathan
    Pages 273-297

  14. Targeting Signal Transducer and Activator of Transcription (STAT) for Anticancer Therapy

    • Fabio P. S. Santos, Inbal Hazan-Halevy, Zeev Estrov
    Pages 299-321

  15. Back Matter

    Pages 323-328
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Keywords

About this book

This book provides an overview of critical components of cell signaling machinery and its role in epithelial morphogenesis, proliferation, invasions and angiogenesis in human cancer and discusses novel types of protein kinase pathways.

Editors and Affiliations

  • , Pharmaceutical Technology, Jadavpur University, Kolkata, India

    Malay Chatterjee

  • , Division of Biochemistry & Chemistry, City University of New York Medical Scho, New York, USA

    Khosrow Kashfi

Bibliographic Information

  • Book Title: Cell Signaling & Molecular Targets in Cancer

  • Editors: Malay Chatterjee, Khosrow Kashfi

  • DOI: https://doi.org/10.1007/978-1-4614-0730-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-0729-4Published: 02 December 2011

  • Softcover ISBN: 978-1-4899-9393-9Published: 03 March 2014

  • eBook ISBN: 978-1-4614-0730-0Published: 02 December 2011

  • Edition Number: 1

  • Number of Pages: XII, 328

  • Topics: Cancer Research, Pharmacology/Toxicology

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